Xiaohai Chen
Overview
Explore the profile of Xiaohai Chen including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
27
Citations
26
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
11.
Yang J, Chen J, Li Q, Xu R, Chen X
Front Pharmacol
. 2024 Sep;
15:1438259.
PMID: 39228528
Lenvatinib is a first-line therapy for the treatment of hepatocellular carcinoma (HCC), an active multi-target tyrosine kinase inhibitor (TKI). The interaction between Traditional Chinese Medicine (TCM) and chemicals has increasingly...
12.
Wu H, Xie S, Chen X, Xia H, Shen Y, Xu R, et al.
J Pharm Biomed Anal
. 2024 Aug;
249:116383.
PMID: 39096626
Fuzuloparib is a novel orally bioactive poly-ADP-ribose polymerase inhibitor (PARPi), which was approved by the Chinese Regulatory Agency (CRA) in 2020 for the treatment of platinum-sensitive recurrent ovarian, fallopian tube,...
13.
Hu Y, Ye Z, Wu H, Chen X, Xia H, Cai J, et al.
Chem Biol Interact
. 2024 Jul;
399:111154.
PMID: 39025286
Clothianidin, classified as a second-generation neonicotinoid, has achieved extensive application due to its high efficacy against insect pests. This broad-spectrum usage has resulted in its frequent detection in environmental surveys....
14.
Shen Y, Chen X, Wu H, Xia H, Xu R
Chem Biol Interact
. 2024 Jul;
399:111146.
PMID: 39002878
Apixaban is an oral anticoagulant that directly inhibits the target Factor Xa (FXa). In this study, we focused on the in vivo and in vitro effects of adagrasib and asciminib...
15.
Ni J, Chen X, Chen N, Yan Y, Wu Y, Li B, et al.
J Ethnopharmacol
. 2024 May;
331:118336.
PMID: 38750983
Ethnopharmacological Relevance: Dendrobium officinale Kimura et Migo, known as "Tiepi Shihu" in traditional Chinese medicine, boasts an extensive history of medicinal use documented in the Chinese Pharmacopoeia. "Shen Nong Ben...
16.
Chen L, Chen X, Liu J, Yang J, Xu R
Chem Biol Interact
. 2024 May;
397:111041.
PMID: 38719170
Abrocitinib is approved to treat moderate-to-severe atopic dermatitis and eliminated mainly through cytochrome P450 (CYP450) enzyme. Two commonly used antidepressants, amitriptyline and fluoxetine, could inhibit the activities of CYP2C19 and...
17.
Shi L, Hu J, Wu H, Shen Y, Chen X, Weng Q, et al.
J Pharm Biomed Anal
. 2024 Mar;
243:116079.
PMID: 38471255
This aim of the work was to establish an acceptable sensitive assay based on ultra-performance liquid chromatography tandem mass spectrometry (UPLC-MS/MS) for quantitatively analyzing the plasma concentrations of iguratimod (IGR)...
18.
Yu Y, Hu J, Chen X, Wu H, Wang A, Tang C
BMC Chem
. 2024 Feb;
18(1):37.
PMID: 38378603
Broad-spectrum histone deacetylase inhibitors (HDACi) have excellent anti-tumor effects, such as abexinostat, which was a novel oral HDACi that was widely used in clinical treatment. The purpose of this study...
19.
Liu J, Chen X, Lv H, He S, Fan Y
Biotechnol Appl Biochem
. 2023 Dec;
71(2):256-263.
PMID: 38053502
Osteoporosis is with porous bones, which refers to a decrease in the bone mineral density and weakens the bones to become brittle. Osteoporosis often progresses without any pain or symptoms...
20.
Chen J, Shen Y, Xia H, Chen X, Xu R, Lin G, et al.
Front Pharmacol
. 2023 Nov;
14:1265252.
PMID: 38026954
Lacosamide, a third-generation novel antiepileptic drug, was first approved in 2008 as an adjunct to partial seizures. In 2014, the U.S. Food and Drug Administration (FDA) approved it as a...