Xiao Le Xu
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Explore the profile of Xiao Le Xu including associated specialties, affiliations and a list of published articles.
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11
Citations
170
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Recent Articles
1.
Li C, Wu R, Xie Q, Wang F, Le Xu X
J Cardiovasc Pharmacol
. 2025 Feb;
PMID: 39970127
Procyanidin B2 (PB2) is a prominent procyanidin isomer. Its effects and mechanisms in cardiac remodeling are not fully understood. Peroxisome proliferator-activated receptor gamma (PPAR-γ) plays a crucial role in regulating...
2.
Wu R, Wang C, Wang J, Le Xu X
Eur J Pharmacol
. 2023 Nov;
961:176137.
PMID: 37939989
Reverse cholesterol transport (RCT) offers a practical approach to mitigating atherosclerosis. Paeoniflorin, a monoterpenoid glycoside found in plants of the Paeoniaceae family, has shown various effects on cardiovascular and liver...
3.
Wang C, Wang J, Cao J, Xu J, Wu R, Le Xu X
Phytomedicine
. 2022 Mar;
99:154017.
PMID: 35276590
Background: 2,3,4',5-tetrahydroxystilbene-2-O-β-d-glycoside (TSG), the main active polyphenolic component of Polygonum multiflorum, possesses many pharmacological activities. Its anti-aging effect influences a variety of tissues with diverse mechanisms. However, the effectiveness and...
4.
Zeng Y, Wang C, Xu J, Le Xu X
Biochem Pharmacol
. 2021 Apr;
188:114559.
PMID: 33872571
Retinoid X receptor beta (RXRβ) has been poorly studied in atherosclerosis. The aim of the present study is to explore the function of RXRβ in oxidized low density lipoprotein (ox-LDL)-induced...
5.
Hua Y, Zeng Y, Xu J, Le Xu X
Phytomedicine
. 2020 Nov;
81:153412.
PMID: 33234364
Background: Naringenin is naturally isolated from citrus fruits possessing many pharmacological activities. However, little is known about the effect of naringenin on nonalcoholic steatohepatitis (NASH) in the model of metabolic...
6.
Zeng Y, Xu J, Hua Y, Peng Y, Le Xu X
Atherosclerosis
. 2020 Jun;
305:1-9.
PMID: 32585463
Background And Aims: Murine double minute-2 (MDM2) has been poorly studied in cardiovascular diseases. The aim of the present study was to determine the biological role of MDM2 in inflammation...
7.
Zeng Y, Hua Y, Wang W, Zhang H, Le Xu X
Biochem Pharmacol
. 2020 Mar;
175:113927.
PMID: 32217100
Dihydromyricetin (DMY) is the most abundant flavonoid in Ampelopsis grossedentata possessing many pharmacological activities. But less is known about its protective effect against nonalcoholic steatohepatitis (NASH) in the context of...
8.
Peng Y, Xu J, Zeng Y, Chen L, Le Xu X
Phytomedicine
. 2019 May;
62:152935.
PMID: 31085374
Background: Polydatin has been recently shown to possess extensive cardiovascular pharmacological activities. However, its protective effect against atherosclerosis in vivo remains poorly understood. The aim of the present study was...
9.
Zeng Y, Peng Y, Tang K, Wang Y, Zhao Z, Wei X, et al.
Biomed Pharmacother
. 2018 Mar;
101:543-552.
PMID: 29505925
As the most abundant flavonoid in Ampelopsis grossedentata, the protective effects of dihydromyricetin on atherosclerosis have been well established, yet the detailed mechanisms are not fully understood. The aim of...
10.
Liu T, Zeng Y, Tang K, Chen X, Zhang W, Le Xu X
Atherosclerosis
. 2017 May;
262:39-50.
PMID: 28500865
Background And Aims: Dihydromyricetin, the most abundant flavonoid in Ampelopsis grossedentata, exerts numerous pharmacological activities, including anti-inflammatory, antioxidant, hepatoprotective, and lipid regulatory activities; however, its protective effect against atherosclerosis remains...