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Xiao-Wen Qian

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Articles 12
Citations 68
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Recent Articles
1.
Gao X, Bian Z, Qiao X, Qian X, Li J, Shen G, et al.
Front Pharmacol . 2022 Aug; 13:933739. PMID: 35979231
Cyclosporine (CsA) is a component of the first-line treatment for acquired aplastic anemia (acquired AA) in pediatric patients. This study aimed to develop a population pharmacokinetic (PK) model of CsA...
2.
Tang W, Hu W, Huang Y, Wu B, Peng X, Zhai X, et al.
World J Clin Cases . 2021 Aug; 9(21):5873-5888. PMID: 34368306
Background: Patients with lipopolysaccharide (LPS)-responsive beige-like anchor protein (LRBA) deficiency have a variety of clinical symptoms, but there is no apparent genotype-phenotype correlation, and patients carrying the same mutations may...
3.
Gao X, Qian X, Zhu X, Yu Y, Miao H, Meng J, et al.
Front Pharmacol . 2021 Jul; 12:701452. PMID: 34326772
High-dose methotrexate (HD-MTX) is widely used in pediatric acute lymphoblastic leukemia (ALL) treatment regimens. In this study, we aimed to develop a population pharmacokinetic (PK) model of HD-MTX in Chinese...
4.
Zhang H, Wang H, Qian X, Zhu X, Miao H, Yu Y, et al.
Transl Pediatr . 2020 Mar; 9(1):4-12. PMID: 32154130
Background: Acute lymphoblastic leukemia (ALL) is the most common malignancy in children, while relapse and refractory ALL remains a leading cause of death in children. However, paired ALL samples of...
5.
Zhang H, Wang H, Qian X, Fan C, Li J, Miao H, et al.
Ann Transl Med . 2019 Sep; 7(14):296. PMID: 31475166
Background: Acute lymphoblastic leukemia (ALL), the most common childhood malignancy, is characterized by molecular aberrations. Recently, genetic profiling has been fully investigated on ALL; however, the interaction between its genetic...
6.
Li J, Zhai X, Wang H, Qian X, Miao H, Zhu X
Med Sci Monit . 2016 Dec; 22:4992-5002. PMID: 27991481
BACKGROUND The aim of this study was to investigate the diagnostic and prognostic value of microRNA (miRNA)-21, miRNA-23a, and miRNA-125b in Burkitt lymphoma (BL) in children. MATERIAL AND METHODS We...
7.
Li J, Wang X, Zhai X, Wang H, Qian X, Miao H, et al.
Int J Clin Exp Med . 2015 Jul; 8(4):6109-13. PMID: 26131212
Objective: The present study aims to investigate the correlation of polymorphisms of SLCO1B1 gene with the toxicity during therapy with the high-dose methotrexate (MTX) chemotherapy in childhood acute lymphoblastic leukemia....
8.
Guo X, Zhai X, Qian X, Wang H, Fan C
Zhongguo Shi Yan Xue Ye Xue Za Zhi . 2015 May; 23(2):312-7. PMID: 25948177
Objective: To further understand the cytogenetic characteristics of pediatric acute lymphoblastic leukemia (ALL). Methods: Cytogenetic abnormalities of 163 children with newly diagnosed ALL (0-17 years of age) were evaluated by...
9.
He M, An Y, Gao Y, Qian X, Li G, Qian J
Mol Vis . 2014 May; 20:545-52. PMID: 24791139
Purpose: Retinoblastoma (RB) sets the paradigm for hereditary cancer syndromes, for which medical care can change depending on the results of genetic testing. In this study, we screened constitutional mutations...
10.
Gao Y, Pan C, Tang J, Lu F, Chen J, Xue H, et al.
Pediatr Blood Cancer . 2013 Nov; 61(4):659-63. PMID: 24243691
Background: This retrospective cohort study analysed the clinical characteristics and outcomes of patients with childhood lymphoblastic lymphoma (LBL) treated in Shanghai, China. Procedure: From 2001 to 2010, 108 evaluable patients...