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Xiao-Min Niu

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Articles 19
Citations 222
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Recent Articles
1.
Hou X, Xu Y, Sun T, Gong Y, Li X, Jin G, et al.
Sci China Life Sci . 2025 Jan; 68(3):859-870. PMID: 39856442
To elucidate the process of adaptation, particularly the traits subject to natural selection and the molecular mechanisms underlying their natural variation, is one of the primary objectives of evolutionary biology....
2.
Fu Q, Ma L, Niu X, Zhao H, Ge X, Jin H, et al.
World J Gastrointest Oncol . 2024 Jul; 16(6):2842-2861. PMID: 38994129
Background: Gastrointestinal neoplasm (GN) significantly impact the global cancer burden and mortality, necessitating early detection and treatment. Understanding the evolution and current state of research in this field is vital....
3.
Wang C, Dai H, Tan Y, Yang D, Niu X, Han L, et al.
Pharmaceuticals (Basel) . 2024 Feb; 17(2). PMID: 38399453
Immunotherapy has shown clinical benefit in patients with non-small-cell lung cancer (NSCLC). Due to the limited response of monotherapy, combining immune checkpoint inhibitors (ICIs) and chemotherapy is considered a treatment...
4.
Jiang J, Xu Y, Zhang Z, Chen J, Niu X, Hou X, et al.
Plant Cell . 2023 Nov; 36(4):840-862. PMID: 38036296
Genetic load refers to the accumulated and potentially life-threatening deleterious mutations in populations. Understanding the mechanisms underlying genetic load variation of transposable element (TE) insertion, a major large-effect mutation, during...
5.
He X, Guo Z, Niu X
Front Oncol . 2023 Feb; 13:1087790. PMID: 36761951
Diffuse hemangiomatosis of the liver and spleen is rare. Currently, few studies are available on diffuse hepatic and splenic hemangiomatosis accompanied by Kasabach-Merritt syndrome (KMS). The conserved telomere maintenance component...
6.
Yuan Z, Niu X, Liu X, Fu H, Xue T, Koo C, et al.
Transl Lung Cancer Res . 2021 Sep; 10(8):3671-3681. PMID: 34584865
Background: The intravoxel incoherent motion (IVIM) method of magnetic resonance imaging (MRI) analysis can provide information regarding many physiological and pathological processes. This study aimed to investigate whether IVIM-derived parameters...
7.
Lu S, Zhou J, Niu X, Zhou J, Jian H, Yin H, et al.
Transl Lung Cancer Res . 2021 Mar; 10(2):839-854. PMID: 33718026
Background: Fruquintinib is an oral vascular endothelial growth factor receptor inhibitor. Previous gefitinib studies with anti-angiogenics show promising efficacy. This phase II trial assessed efficacy and safety of fruquintinib in...
8.
Xu Y, Niu X, Li X, He W, Chen J, Zou Y, et al.
Plant Cell . 2019 Mar; 31(5):1012-1025. PMID: 30886128
According to the less-is-more hypothesis, gene loss is an engine for evolutionary change. Loss-of-function (LoF) mutations resulting in the natural knockout of protein-coding genes not only provide information about gene...
9.
Niu X, Xu Y, Li Z, Bian Y, Hou X, Chen J, et al.
Proc Natl Acad Sci U S A . 2019 Mar; 116(14):6908-6913. PMID: 30877258
Rapid phenotypic changes in traits of adaptive significance are crucial for organisms to thrive in changing environments. How such phenotypic variation is achieved rapidly, despite limited genetic variation in species...
10.
Yang L, Wang H, Hou X, Zou Y, Han T, Niu X, et al.
Plant Cell . 2018 May; 30(6):1322-1336. PMID: 29764984
Flowering time is an adaptive life history trait. , a close relative of and a young species, displays extensive variation for flowering time but low standing genetic variation due to...