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Xiao-Jun Yu

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Articles 77
Citations 209
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Recent Articles
1.
Liu X, Li J, Zheng Y, Xiao X, Yu X
Fa Yi Xue Za Zhi . 2025 Feb; 40(5):439-446. PMID: 39992335
Objectives: To investigate the occurrence and mechanism of acute Karoshi and explore its forensic identification. Methods: SD rats were divided into the control group (=15) and experimental groups (=45, acute...
2.
Yu X, Zou P, Li T, Bai X, Wang S, Guan J, et al.
Cell Biol Toxicol . 2025 Jan; 41(1):33. PMID: 39825191
This study delved into the molecular mechanisms underlying mechanical stress-induced intervertebral disc degeneration (msi-IDD) through single-cell and high-throughput transcriptome sequencing in mouse models and patient samples. Results exhibited an upsurge...
3.
Sun M, Li S, Guo Y, Zhou J, Fu D, Hua X, et al.
Neurosurg Rev . 2024 Oct; 47(1):763. PMID: 39382734
Epithelioid glioblastoma (Ep-GBM) is a rare variant of glioblastoma characterized by a high recurrence rate and poor prognosis. Currently, there is no established standard treatment for Ep-GBM. Therefore, we identified...
4.
Yu X, Zhao Y, Abudouaini H, Zou P, Li T, Bai X, et al.
J Nanobiotechnology . 2024 Sep; 22(1):556. PMID: 39267105
Methods: Single-cell transcriptomics and high-throughput transcriptomics were used to screen factors significantly correlated with intervertebral disc degeneration (IDD). Expression changes of CFIm25 were determined via RT-qPCR and Western blot. NP...
5.
Yu X, Bai X, Qu Y, Wang S, Zhang J, Yang W, et al.
ACS Biomater Sci Eng . 2024 Jul; 10(8):4839-4854. PMID: 39079050
Intervertebral disc degeneration (IVDD) is a prevalent chronic condition causing spinal pain and functional impairment. This study investigates the role of extracellular vesicles (EVs) derived from human umbilical cord mesenchymal...
6.
Shi J, Hu K, Li X, Ge Y, Yu X, Zhao J
Cell Commun Signal . 2024 Jan; 22(1):28. PMID: 38200540
Background: Bisphenol A (BPA) levels are high in women with polycystic ovary syndrome (PCOS). The mechanism by which BPA induces abnormal glucose metabolism in PCOS patients is largely unknown. Methods:...
7.
Dai X, Deng L, Xiao X, Yu X, Lv J, Xiong H, et al.
Mitochondrial DNA B Resour . 2023 Dec; 8(12):1401-1405. PMID: 38130731
We performed the first sequencing of the complete mitogenome of by high-throughput sequencing. A circular DNA molecule of 15,219 bp in size, encoding 2 rRNAs, 22 tRNAs, and 13 PCGs,...
8.
Xu Y, Liu R, Yu X, Liu X, Zhang X, Jiang Z, et al.
Phytochem Anal . 2023 Sep; 35(1):146-162. PMID: 37731278
Introduction: Dajianzhong decoction (DJZD), a classic famous prescription, has a long history of medicinal application. Modern studies have demonstrated its clinical utility in the treatment of postoperative ileus (POI). But...
9.
Lai S, Hu K, Zhou X, Li X, Yu X, Shi J, et al.
Am J Reprod Immunol . 2023 May; 90(1):e13712. PMID: 37165740
Problem: Immunomodulation profoundly affects the process of human implantation. Trophoblast cell-derived microparticles (Tr-MPs) may activate specific T cells to attack trophoblast cells, thus potentially acting as an immunocontraceptive vaccine. The...
10.
Yu X, Wang Y, Lu R, Guo X, Qu Y, Wang S, et al.
Mol Med . 2023 Mar; 29(1):30. PMID: 36858954
Background: Accumulating evidence indicates that intervertebral disc degeneration (IDD) is associated with diabetes mellitus (DM), while the underlying mechanisms still remain elusive. Herein, the current study sought to explore the...