Xiangjun He
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Explore the profile of Xiangjun He including associated specialties, affiliations and a list of published articles.
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41
Citations
581
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Recent Articles
1.
Wang L, Wang Y, He X, Mo Z, Zhao M, Liang X, et al.
Cell Rep Med
. 2025 Jan;
6(1):101889.
PMID: 39793572
Clinical application of autologous chimeric antigen receptor (CAR)-T cells is complicated by limited targeting of cancer types, as well as the time-consuming and costly manufacturing process. We develop CD70-targeted, induced...
2.
Liu X, Luo J, Chen J, Huang P, He G, Ye X, et al.
CNS Neurosci Ther
. 2024 Nov;
30(11):e70113.
PMID: 39500736
Background: The oxidative stress and neuroinflammation are important factors in acute ischemic stroke (AIS). Our former study showed the 1,2,4- triazole derivative (SYS18) had obviously neuroprotection by anti- oxidative stress...
3.
He X, Dong M, Xiong H, Zhu Y, Ping F, Wang B, et al.
BMC Pulm Med
. 2024 Aug;
24(1):420.
PMID: 39210309
Background: Postoperative pulmonary complication (PPC) is a leading cause of mortality and poor outcomes in postoperative patients. No studies have enrolled intensive care unit (ICU) patients after noncardiac thoracic surgery,...
4.
Ma X, Dai L, Tan C, Li J, He X, Wang Y, et al.
Cell Biosci
. 2024 Jul;
14(1):96.
PMID: 39049023
Background: β-catenin, acting as the core effector of canonical Wnt signaling pathway, plays a pivotal role in controlling lineage commitment and the formation of definitive endoderm (DE) during early embryonic...
5.
Zheng Z, Xu L, Gao Y, Dou H, Zhou Y, Feng X, et al.
Microbiol Spectr
. 2024 Apr;
12(7):e0216423.
PMID: 38563791
Importance: ASFV is currently a devastating disease with no effective vaccine or treatment available. Our study introduces a multiplexed CRISPR-Cas system targeting nine specific loci in the ASFV genome. This...
6.
Dai Y, Yang W, Song H, He X, Guan R, Wu Z, et al.
Environ Int
. 2024 Mar;
185:108521.
PMID: 38508052
Electronic cigarettes (e-cigarettes) have rapidly gained popularity as alternatives to traditional combustible cigarettes. However, their long-term health impact remains uncertain. This study aimed to investigate the effects of chronic exposure...
7.
Liu J, Wang Z, Zhou J, Wang J, He X, Wang J
Chin Med J (Engl)
. 2023 May;
136(21):2576-2586.
PMID: 37144734
Background: Steroid receptor-associated and regulated protein (SRARP) suppresses tumor progression and modulates steroid receptor signaling by interacting with estrogen receptors and androgen receptors in breast cancer. In endometrial cancer (EC),...
8.
Lei S, He X, Yang X, Gu X, He Y, Wang J
J Cancer
. 2023 Apr;
14(4):634-645.
PMID: 37057290
Endometrial carcinoma is one of the most common female malignancies worldwide. Based on our preliminary investigation, DUSP1 was identified as a potential biomarker for endometrial carcinoma prognosis, but its function...
9.
He X, Zhong Z, Wang Q, Jia Z, Lu J, Chen J, et al.
Front Pharmacol
. 2023 Mar;
14:1127219.
PMID: 36969870
Cryptotanshinone(CTS), a compound derived from the root of , has been linked to various of diseases, particularly pulmonary fibrosis. In the current study, we investigated the benefit of CTS on...
10.
He X, Zhang Z, Xue J, Wang Y, Zhang S, Wei J, et al.
Nat Commun
. 2022 Nov;
13(1):7275.
PMID: 36434000
AAV-delivered CRISPR/Cas9 (AAV-CRISPR) has shown promising potentials in preclinical models to efficiently insert therapeutic gene sequences in somatic tissues. However, the AAV input doses required were prohibitively high and posed...