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Xiang-Yin Kong

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Articles 18
Citations 220
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Recent Articles
1.
Wang Y, Zhang X, Ma Q, Hu L, Zhang X, Wang Y, et al.
Cell Death Dis . 2021 Jan; 12(1):85. PMID: 33446653
Phosphoinositide-3 kinase alpha-specific inhibitors (PI3Kαi) displayed promising potential for the treatment of esophageal squamous cell carcinoma (ESCC) with frequent activation in PI3K signaling. However, acquired resistance is likely to develop...
2.
Pan X, Chen L, Feng K, Hu X, Zhang Y, Kong X, et al.
Int J Mol Sci . 2019 May; 20(9). PMID: 31052553
Small nucleolar RNAs (snoRNAs) are a new type of functional small RNAs involved in the chemical modifications of rRNAs, tRNAs, and small nuclear RNAs. It is reported that they play...
3.
Yuan F, Zhang Y, Kong X, Cai Y
Biomed Res Int . 2017 Mar; 2017:5741948. PMID: 28293637
Identification of disease genes is a hot topic in biomedicine and genomics. However, it is a challenging problem because of the complexity of diseases. Inflammatory bowel disease (IBD) is an...
4.
Yuan F, Zhang Y, Wan S, Wang S, Kong X
Biomed Res Int . 2015 Nov; 2015:623121. PMID: 26613085
Pancreatic cancer (PC) is a highly malignant tumor derived from pancreas tissue and is one of the leading causes of death from cancer. Its molecular mechanism has been partially revealed...
5.
Zhang P, Chen L, Huang T, Zhang N, Kong X, Cai Y
PLoS One . 2015 Mar; 10(3):e0123147. PMID: 25822500
Gathering vast data sets of cancer genomes requires more efficient and autonomous procedures to classify cancer types and to discover a few essential genes to distinguish different cancers. Because protein...
6.
Zhou Y, Zhang N, Li B, Huang T, Cai Y, Kong X
J Biomol Struct Dyn . 2015 Jan; 33(11):2479-90. PMID: 25616595
Lysine acetylation and ubiquitination are two primary post-translational modifications (PTMs) in most eukaryotic proteins. Lysine residues are targets for both types of PTMs, resulting in different cellular roles. With the...
7.
Li B, You J, Chen L, Zhang J, Zhang N, Li H, et al.
Biomed Res Int . 2013 Jun; 2013:267375. PMID: 23762832
Lung cancer is one of the leading causes of cancer mortality worldwide. The main types of lung cancer are small cell lung cancer (SCLC) and nonsmall cell lung cancer (NSCLC)....
8.
Li B, Niu B, Chen L, Wei Z, Huang T, Jiang M, et al.
PLoS One . 2013 Jun; 8(6):e65207. PMID: 23762317
Acquired immune deficiency syndrome (AIDS) is a severe infectious disease that causes a large number of deaths every year. Traditional anti-AIDS drugs directly targeting the HIV-1 encoded enzymes including reverse...
9.
Huang T, Zhang J, Xu Z, Hu L, Chen L, Shao J, et al.
Biochimie . 2012 Jan; 94(4):1017-25. PMID: 22239951
Longevity is one of the most basic and one of the most essential properties of all living organisms. Identification of genes that regulate longevity would increase understanding of the mechanisms...
10.
Yi X, He Z, Chou K, Kong X
Protein Pept Lett . 2011 Sep; 19(1):79-90. PMID: 21919856
The DNA of all eukaryotic organisms is packaged into nucleosomes (a basic repeating unit of chromatin). A nucleosome consists of histone octamer wrapped by core DNA and linker histone H1...