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Xi Ai

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Articles 33
Citations 408
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Recent Articles
1.
Huang J, Dong S, Wu Y, Yi H, Zhang W, Ai X
Int Heart J . 2024 May; 65(3):466-474. PMID: 38749754
Endothelial cell dysfunction is the main pathology of atherosclerosis (AS). Sirtuin 6 (SIRT6), a deacetylase, is involved in AS progression. This study aimed to investigate the impacts of SIRT6 on...
2.
Wu Y, Yu B, Ai X, Zhang W, Chen W, Laurence A, et al.
Biol Chem . 2024 Jan; 405(4):241-256. PMID: 38270141
We investigated the effects of transcriptional intermediary factor 1γ (TIF1γ) and SMAD4 on the proliferation and liver metastasis of colorectal cancer (CRC) cells through knockdown of TIF1γ and/or SMAD4 and...
3.
Kasper S, Otten S, Squadroni B, Orr-Terry C, Kuang Y, Mussallem L, et al.
Bioeng Transl Med . 2023 Sep; 8(5):e10542. PMID: 37693049
Cyclic peptides are poised to target historically difficult to drug intracellular protein-protein interactions, however, their general cell impermeability poses a challenge for characterizing function. Recent advances in microfluidics have enabled...
4.
Wu Y, Yu B, Zhou J, Shen X, Chen W, Ai X, et al.
BMC Cancer . 2023 Jun; 23(1):511. PMID: 37277714
Background: This study aimed to identify the biological functions, expression modes, and possible mechanisms underlying the relationship between metastatic human hepatocellular carcinoma (HCC) and MicroRNA-188-5p (miR-188) dysregulation using cell lines....
5.
Xing L, Ai X, Ren J, Wang D
Entropy (Basel) . 2021 Oct; 23(10). PMID: 34681998
Network science has been widely applied in theoretical and empirical studies of global value chain (GVC), and many related articles have emerged, forming many more mature and complete analytical frameworks....
6.
Wu Y, Yu B, Chen W, Ai X, Zhang W, Dong W, et al.
Aging (Albany NY) . 2021 Aug; 13(15):19260-19271. PMID: 34341185
SBF2-AS1 is an oncogenic long non-coding RNA (lncRNA). However, its role and mechanism in hepatocellular carcinoma (HCC) is still not completely clear. The HepG2, Hep3B, Bel-7402 and HL-7702 cell lines...
7.
Choy J, Kan Y, Cifelli S, Johnson J, Chen M, Shiao L, et al.
SLAS Discov . 2021 Jul; 26(9):1225-1237. PMID: 34218698
High-throughput phenotypic screening is a key driver for the identification of novel chemical matter in drug discovery for challenging targets, especially for those with an unclear mechanism of pathology. For...
8.
Petrilli W, Adam G, Erdmann R, Abeywickrema P, Agnani V, Ai X, et al.
Cell Chem Biol . 2021 Feb; 28(2):243. PMID: 33607006
No abstract available.
9.
Yi H, Cai B, Ai X, Li K, Song P, Zhang W
Biomed Res Int . 2020 Oct; 2020:2462058. PMID: 33029496
Objective: It is difficult to evaluate the ablation effect immediately after thermal ablation of liver cancer by clinical imaging methods, due to the immediate formation of an annular inflammatory reaction...
10.
Fells J, Ai X, Weinglass A, Feng W, Lei Y, Finley M, et al.
Bioorg Med Chem Lett . 2020 Aug; 30(21):127460. PMID: 32755680
Structure- and ligand-based virtual-screening methods (docking, 2D- and 3D-similarity searching) were analyzed for their effectiveness in virtual screening against FFAR2. To evaluate the performance of these methods, retrospective virtual screening...