Xavier Sanchez-Saez
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Explore the profile of Xavier Sanchez-Saez including associated specialties, affiliations and a list of published articles.
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Articles
16
Citations
198
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Recent Articles
1.
Garcia-Garcia D, Vidal-Gil L, Parain K, Lun J, Audic Y, Chesneau A, et al.
Sci Adv
. 2024 Oct;
10(40):eadp7916.
PMID: 39356769
Unlike mammals, some nonmammalian species recruit Müller glia for retinal regeneration after injury. Identifying the underlying mechanisms may help to foresee regenerative medicine strategies. Using a model of retinitis pigmentosa,...
2.
Martinez-Gil N, Kutsyr O, Fernandez-Sanchez L, Sanchez-Saez X, Albertos-Arranz H, Sanchez-Castillo C, et al.
Int J Mol Sci
. 2023 Nov;
24(22).
PMID: 38003256
Ischemia is the main cause of cell death in retinal diseases such as vascular occlusions, diabetic retinopathy, glaucoma, or retinopathy of prematurity. Although excitotoxicity is considered the primary mechanism of...
3.
Ruiz-Pastor M, Sanchez-Saez X, Kutsyr O, Albertos-Arranz H, Sanchez-Castillo C, Ortuno-Lizaran I, et al.
Cell Death Dis
. 2023 Nov;
14(11):711.
PMID: 37914688
Central areolar choroidal dystrophy is an inherited disorder characterized by progressive choriocapillaris atrophy and retinal degeneration and is usually associated with mutations in the PRPH2 gene. We aimed to generate...
4.
Guardia A, Fernandez A, Seruggia D, Chotard V, Sanchez-Castillo C, Kutsyr O, et al.
Invest Ophthalmol Vis Sci
. 2023 Oct;
64(13):32.
PMID: 37862028
Purpose: We aimed to generate and phenotype a mouse model of foveal hypoplasia, optic nerve decussation defects, and anterior segment dysgenesis (FHONDA), a rare disease associated with mutations in Slc38a8...
5.
Sanchez-Saez X, Ortuno-Lizaran I, Sanchez-Castillo C, Lax P, Cuenca N
Transl Neurodegener
. 2023 May;
12(1):22.
PMID: 37161526
No abstract available.
6.
Sanchez-Saez X, Ortuno-Lizaran I, Sanchez-Castillo C, Lax P, Cuenca N
Transl Neurodegener
. 2023 Apr;
12(1):17.
PMID: 37013599
Background: The main clinical symptoms characteristic of Parkinson's disease (PD) are bradykinesia, tremor, and other motor deficits. However, non-motor symptoms, such as visual disturbances, can be identified at early stages...
7.
Albertos-Arranz H, Martinez-Gil N, Sanchez-Saez X, Noailles A, Monferrer Adsuara C, Remoli Sargues L, et al.
Eye Vis (Lond)
. 2023 Mar;
10(1):12.
PMID: 36855168
Background: Different ocular alterations have been described in patients with coronavirus disease 2019 (COVID-19). Our aim was to determine whether COVID-19 affected retinal cells and establish correlations with clinical parameters....
8.
Martinez-Gil N, Kutsyr O, Noailles A, Fernandez-Sanchez L, Vidal L, Sanchez-Saez X, et al.
Int J Mol Sci
. 2022 Dec;
23(23).
PMID: 36499084
The purinergic receptor P2X7 (P2X7R) is implicated in all neurodegenerative diseases of the central nervous system. It is also involved in the retinal degeneration associated with glaucoma, age-related macular degeneration,...
9.
Martinez-Gil N, Maneu V, Kutsyr O, Fernandez-Sanchez L, Sanchez-Saez X, Sanchez-Castillo C, et al.
Front Neuroanat
. 2022 Oct;
16:984052.
PMID: 36225228
Multiple gene mutations have been associated with inherited retinal dystrophies (IRDs). Despite the spectrum of phenotypes caused by the distinct mutations, IRDs display common physiopathology features. Cell death is accompanied...
10.
Pinilla I, Maneu V, Campello L, Fernandez-Sanchez L, Martinez-Gil N, Kutsyr O, et al.
Antioxidants (Basel)
. 2022 Jun;
11(6).
PMID: 35739983
Inherited retinal dystrophies (IRDs) are a large group of genetically and clinically heterogeneous diseases characterized by the progressive degeneration of the retina, ultimately leading to loss of visual function. Oxidative...