X Grana
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Explore the profile of X Grana including associated specialties, affiliations and a list of published articles.
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Articles
33
Citations
987
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Recent Articles
1.
Calbo J, Serna C, Garriga J, Grana X, Mazo A
Cell Death Differ
. 2004 Aug;
11(10):1055-65.
PMID: 15309028
Restitution of lost tumor-suppressor activities may be a promising strategy to target specifically cancer cells. However, the action of ectopically expressed tumor-suppressor genes depends on genetic background of tumoral cells....
2.
Parreno M, Garriga J, Limon A, Albrecht J, Grana X
Oncogene
. 2001 Aug;
20(35):4793-806.
PMID: 11521191
We have previously shown that the adenoviral 12S E1A protein modulates the phosphorylation status of p130 and p107 without apparent changes in the cell cycle dependent phosphorylation of the retinoblastoma...
3.
Parreno M, Garriga J, Limon A, Mayol X, Beck Jr G, Moran E, et al.
J Virol
. 2000 Mar;
74(7):3166-76.
PMID: 10708433
The phosphorylation status of the pRB family of growth suppressor proteins is regulated in a cell cycle entry-, progression-, and exit-dependent manner in normal cells. We have shown previously that...
4.
Role of the retinoblastoma protein family, pRB, p107 and p130 in the negative control of cell growth
Grana X, Garriga J, Mayol X
Oncogene
. 1999 Jan;
17(25):3365-83.
PMID: 9916999
The retinoblastoma family of proteins, also known as pocket proteins, includes the product of the retinoblastoma susceptibility gene and the functionally and structurally related proteins p107 and p130. Pocket proteins...
5.
Garriga J, Peng J, Parreno M, Price D, Henderson E, Grana X
Oncogene
. 1999 Jan;
17(24):3093-102.
PMID: 9872325
Cyclin T1 has been identified recently as a regulatory subunit of CDK9 and as a component of the transcription elongation factor P-TEFb. Cyclin T1/CDK9 complexes phosphorylate the carboxy terminal domain...
6.
Fujinaga K, Cujec T, Peng J, Garriga J, Price D, Grana X, et al.
J Virol
. 1998 Aug;
72(9):7154-9.
PMID: 9696809
By binding to the transactivation response element (TAR) RNA, the transcriptional transactivator (Tat) from the human immunodeficiency virus increases rates of elongation rather than initiation of viral transcription. Two cyclin-dependent...
7.
Garriga J, Limon A, Mayol X, Rane S, Albrecht J, Reddy E, et al.
Biochem J
. 1998 Jul;
333 ( Pt 3):645-54.
PMID: 9677324
In the present study we have analysed the regulation of pocket protein expression and post-transcriptional modifications on cell proliferation and differentiation, both in vivo and in vitro. There are marked...
8.
Jaumot M, Estanol J, Casanovas O, Grana X, Agell N, Bachs O
Biochem Biophys Res Commun
. 1998 Jan;
241(2):434-8.
PMID: 9425288
We report here experimental evidence indicating that the p21CIP, the universal inhibitor of cyclin-dependent protein kinases, general inhibitor CDKs is a substrate oof cyclin A-cdk2. The evidence comes from phosphorylation...
9.
Mayol X, Grana X
Front Biosci
. 1998 Jan;
3:d11-24.
PMID: 9405335
Pocket proteins, including the retinoblastoma susceptibility gene product (pRB) and the related proteins p107 and p130, function at cell cycle regulatory steps that link cyclin/CDK-integrated positive and negative growth signals...
10.
Mayol X, Grana X
Prog Cell Cycle Res
. 1997 Jan;
3:157-69.
PMID: 9580269
The mammalian cell cycle engine, which is composed of cyclin/CDK holoenzymes, controls the progression throughout the cell cycle by regulating, at least in part, the transcription of two types of...