Wuyan Zhang
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Explore the profile of Wuyan Zhang including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
359
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Recent Articles
1.
Tourdot S, Vazquez-Abad M, Cox D, Cai C, Wang K, Zhang W, et al.
Front Immunol
. 2025 Mar;
15:1457993.
PMID: 40084239
Introduction: Unwanted immune responses (UIRs) to biologics can negatively impact treatment efficacy and pharmacokinetics and/or induce adverse events (AEs). We characterized the UIR profile of adalimumab (ADL) using data from...
2.
Hammond J, Yunis C, Fountaine R, Luscan G, Burr A, Zhang W, et al.
N Engl J Med
. 2024 Jul;
391(3):224-234.
PMID: 39018532
Background: Clinical trials of treatments for coronavirus disease 2019 (Covid-19) have not shown a significant benefit of postexposure prophylaxis. Methods: We conducted a phase 2-3 double-blind trial to assess the...
3.
Fleischmann R, Saikali W, Lakhanpal S, Alvarez D, Cox D, Ianos C, et al.
Lancet Rheumatol
. 2024 Jan;
5(9):e532-e541.
PMID: 38251497
Background: An adalimumab biosimilar with an interchangeability designation could increase access to effective treatment for more patients. We aimed to assess the interchangeability of adalimumab biosimilar PF-06410293 (adalimumab-afzb) and reference...
4.
Kay J, Bock A, Rehman M, Zhang W, Zhang M, Iikuni N, et al.
RMD Open
. 2022 Sep;
8(2).
PMID: 36180101
Objectives: This exploratory analysis investigated the potential use of the multibiomarker disease activity (MBDA) score to support biosimilarity assessments using data from two randomised controlled trials (RCTs) of biosimilar infliximab...
5.
Fleischmann R, Bock A, Zhang W, Godfrey C, Vranic I, Cronenberger C, et al.
Rheumatol Ther
. 2022 Mar;
9(3):839-850.
PMID: 35304684
Introduction: The aim of this sub-study was to evaluate injection success of patients with rheumatoid arthritis (RA) and their caregivers administering the adalimumab (ADL) biosimilar, PF-06410293 (ADL-PF: adalimumab-afzb; Abrilada/Amsparity/Xilbrilada) by...
6.
Fleischmann R, Alvarez D, Bock A, Cronenberger C, Vranic I, Zhang W, et al.
Arthritis Res Ther
. 2021 Sep;
23(1):248.
PMID: 34563243
Background/objective: REFLECTIONS B538-02 is a randomized, double-blind comparative study of the adalimumab (ADL) biosimilar PF-06410293, (ADL-PF), and reference ADL sourced from the European Union (ADL-EU) in patients with active RA....
7.
Fleischmann R, Alvarez D, Bock A, Cronenberger C, Vranic I, Zhang W, et al.
RMD Open
. 2021 Apr;
7(2).
PMID: 33883254
Objective: To investigate the efficacy, safety, immunogenicity and pharmacokinetics of biosimilar adalimumab (ADL) PF-06410293 (ADL-PF; adalimumab-afzb) versus EU-sourced reference ADL (ADL-EU) in patients with active rheumatoid arthritis (RA) on longer-term...
8.
Akizawa T, Akiba T, Hirakata H, Kinugasa E, Tominaga Y, Fukagawa M, et al.
Ther Apher Dial
. 2014 Nov;
19(3):225-34.
PMID: 25363733
Secondary hyperparathyroidism (SHPT) is one of the major complications of chronic kidney disease (CKD) and is associated with elevated serum intact parathyroid hormone (iPTH). Calcitriol, a non-selective vitamin D receptor...
9.
Marek G, Katz D, Meier A, Greco 4th N, Zhang W, Liu W, et al.
Alzheimers Dement
. 2014 Jan;
10(5 Suppl):S364-73.
PMID: 24418055
Background: In this study we assessed increased cortisol in Alzheimer's disease (AD) patients. The selective 11-β-hydroxysteroid dehydrogenase type 1 (HSD-1) inhibitor ABT-384 blocked regeneration of active cortisol and this tests...
10.
Tamez H, Zoccali C, Packham D, Wenger J, Bhan I, Appelbaum E, et al.
Am Heart J
. 2012 Dec;
164(6):902-9.e2.
PMID: 23194491
Background: Left atrial enlargement, a sensitive integrator of left ventricular diastolic function, is associated with increased cardiovascular morbidity and mortality. Vitamin D is linked to lower cardiovascular morbidity, possibly modifying...