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Wouter Bult

Explore the profile of Wouter Bult including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 16
Citations 311
Followers 0
Related Specialties
Pharmacology
General Medicine
Pharmacy
Top 10 Co-Authors
Daan J Touw
Alfred D van het Schip
J Frank W Nijsen
Wim E Hennink
Maarten W Nijsten
Frank Doesburg
Chris J G Bakker
Peter R Seevinck
Willem Dieperink
Karina Meijer
Published In
Pharm Res
PLoS One
J Exp Clin Cancer Res
Semin Thromb Hemost
J Vasc Access
Affiliations
Soon will be listed here.
Recent Articles
1.
Tacrolimus Variability and Clinical Outcomes in the Early Post-lung Transplantation Period: Oral Versus Continuous Intravenous Administration
van Dommelen J, Grootjans H, Uijtendaal E, Ruigrok D, Luijk B, van Luin M, et al.
Clin Pharmacokinet . 2024 Apr; 63(5):683-693. PMID: 38581638
Background And Objective: High variability in tacrolimus pharmacokinetics directly after lung transplantation (LuTx) may increase the risk for acute kidney injury (AKI) and transplant rejection. The primary objective was to...
2.
A fast and simple method for the simultaneous analysis of midazolam, 1-hydroxymidazolam, 4-hydroxymidazolam and 1-hydroxymidazolam glucuronide in human serum, plasma and urine
Wessels A, Bolhuis M, Bult W, Nijsten M, Kneyber M, Touw D
J Chromatogr B Analyt Technol Biomed Life Sci . 2021 Jan; 1162:122476. PMID: 33385770
For the quantification of the sedative and anesthetic drug midazolam and its main (active) metabolites 1-hydroxymidazolam, 4-hydroxymidazolam and 1-hydroxymidazolam glucuronide in human serum, human EDTA plasma, human heparin plasma and...
3.
Towards more efficient use of intravenous lumens in multi-infusion settings: development and evaluation of a multiplex infusion scheduling algorithm
Doesburg F, Oelen R, Renes M, Bult W, Touw D, Nijsten M
BMC Med Inform Decis Mak . 2020 Sep; 20(1):206. PMID: 32878609
Background: Multi-drug intravenous (IV) therapy is one of the most common medical procedures used in intensive care units (ICUs), operating rooms, oncology wards and many other hospital departments worldwide. As...
4.
Quantitative assessment of required separator fluid volume in multi-infusion settings
Doesburg F, Middendorp D, Dieperink W, Bult W, Nijsten M, Touw D
J Vasc Access . 2020 May; 21(6):945-952. PMID: 32364801
Background: Administering a separator fluid between incompatible solutions can optimize the use of intravenous lumens. Factors affecting the required separator fluid volume to safely separate incompatible solutions are unknown. Methods:...
5.
Low Dose Low-Molecular-Weight Heparin for Thrombosis Prophylaxis: Systematic Review with Meta-Analysis and Trial Sequential Analysis
Eck R, Bult W, Wetterslev J, Gans R, Meijer K, van der Horst I, et al.
J Clin Med . 2019 Nov; 8(12). PMID: 31766453
International guidelines recommend low-molecular-weight heparin (LMWH) as first-line pharmacological option for the prevention of venous thromboembolism (VTE) in many patient categories. Guidance on the optimal prophylactic dose is lacking. We...
6.
Continuous versus intermittent infusion of cefotaxime in critically ill patients: a randomized controlled trial comparing plasma concentrations
Aardema H, Bult W, Hateren K, Dieperink W, Touw D, Alffenaar J, et al.
J Antimicrob Chemother . 2019 Nov; 75(2):441-448. PMID: 31697336
Background: In critical care patients, reaching optimal β-lactam concentrations poses challenges, as infections are caused more often by microorganisms associated with higher MICs, and critically ill patients typically have an...
7.
Intermediate Dose Low-Molecular-Weight Heparin for Thrombosis Prophylaxis: Systematic Review with Meta-Analysis and Trial Sequential Analysis
Eck R, Bult W, Wetterslev J, Gans R, Meijer K, Keus F, et al.
Semin Thromb Hemost . 2019 Oct; 45(8):810-824. PMID: 31622991
Different doses of low-molecular-weight heparin (LMWH) are registered and used for thrombosis prophylaxis. We assessed benefits and harms of thrombosis prophylaxis with a predefined intermediate-dose LMWH compared with placebo or...
8.
In vitro evaluation of an intravenous microdialysis catheter for therapeutic drug monitoring of gentamicin and vancomycin
van der Mast J, Nijsten M, Alffenaar J, Touw D, Bult W
Pharmacol Res Perspect . 2019 Jul; 7(4):e00483. PMID: 31333845
A central venous catheter with a built-in microdialysis membrane is available for continuous lactate and glucose monitoring in the intensive care unit (ICU). As this catheter might also be suitable...
9.
Improved usability of a multi-infusion setup using a centralized control interface: A task-based usability test
Doesburg F, Cnossen F, Dieperink W, Bult W, de Smet A, Touw D, et al.
PLoS One . 2017 Aug; 12(8):e0183104. PMID: 28800617
The objective of this study was to assess the usability benefits of adding a bedside central control interface that controls all intravenous (IV) infusion pumps compared to the conventional individual...
10.
Adenosine dry powder inhalation for bronchial challenge testing, part 2: proof of concept in asthmatic subjects
Lexmond A, van der Wiel E, Hagedoorn P, Bult W, Frijlink H, Ten Hacken N, et al.
Eur J Pharm Biopharm . 2014 May; 88(1):148-52. PMID: 24780441
Adenosine is an indirect stimulus to assess bronchial hyperresponsiveness (BHR(2)) in asthma. Bronchial challenge tests are usually performed with nebulised solutions of adenosine 5'-monophosphate (AMP(3)). The nebulised AMP test has...