Wongeun Lee
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Explore the profile of Wongeun Lee including associated specialties, affiliations and a list of published articles.
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10
Citations
171
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Recent Articles
1.
Kim D, Synn C, Lee W, Jo H, Lee C, Lee S, et al.
Mol Cancer Ther
. 2024 Dec;
24(3):354-369.
PMID: 39632711
Various combination therapies have been investigated to overcome the limitations of using immune checkpoint inhibitors. However, determining the optimal combination therapy remains challenging. To overcome the therapeutic limitation, we conducted...
2.
Lee W, Kim D, Synn C, Lee H, Park S, Jung D, et al.
Front Oncol
. 2022 Mar;
12:821391.
PMID: 35356198
A recently developed treatment strategy for lung cancer that combines immune checkpoint inhibitors with chemotherapy has been applied as a standard treatment for lung adenocarcinoma (LUAD) and lung squamous cell...
3.
Synn C, Kim S, Lee H, Kim M, Kim J, Lee J, et al.
Clin Transl Immunology
. 2022 Jan;
11(1):e1364.
PMID: 35003748
Objectives: AXL-mediated activation of aberrant tyrosine kinase drives various oncogenic processes and facilitates an immunosuppressive microenvironment. We evaluated the anti-tumor and anti-metastatic activities of SKI-G-801, a small-molecule inhibitor of AXL,...
4.
Synn C, Kim D, Kim J, Byeon Y, Kim Y, Yun M, et al.
Yonsei Med J
. 2021 Dec;
63(1):42-55.
PMID: 34913283
Purpose: Agonists of the stimulator of interferon genes (STING) play a key role in activating the STING pathway by promoting the production of cytokines. In this study, we investigated the...
5.
Lim H, Yang T, Lee W, Park S
Biomedicines
. 2021 Aug;
9(8).
PMID: 34440100
There is growing evidence that myeloid-derived suppressor cells (MDSCs) are directly involved in all stages leading to metastasis. Many mechanisms for this effect have been proposed, but mechanisms of coregulation...
6.
Ahn B, So J, Synn C, Kim T, Kim J, Byeon Y, et al.
Eur J Cancer
. 2021 Jun;
153:179-189.
PMID: 34182269
Objective: Anti-programmed death (PD)-1 therapy confers sustainable clinical benefits for patients with non-small-cell lung cancer (NSCLC), but only some patients respond to the treatment. Various clinical characteristics, including the PD-ligand...
7.
Pyo K, Lim S, Park C, Jo H, Kim J, Yun M, et al.
J Immunother Cancer
. 2020 Jul;
8(2).
PMID: 32727812
Background: is a distinct molecular entity that is highly sensitive to ALK tyrosine kinase inhibitors (TKIs). Immune checkpoint inhibitors (ICIs) have not proved efficacy in -positive non-small cell lung cancer...
8.
Lee C, Lee W, Cho S, Park S
Int J Mol Sci
. 2018 Mar;
19(3).
PMID: 29543758
Myeloid-derived suppressor cells (MDSCs) regulate T cell immunity, and this population is a new therapeutic target for immune regulation. A previous study showed that transforming growth factor-β (TGF-β) is involved...
9.
Han D, Nam S, Song J, Lee W, Kang T
J Phys Ther Sci
. 2017 Nov;
29(10):1852-1855.
PMID: 29184305
[Purpose] The purpose of this study is to research the most effective knee flexion angle and ground condition in the squat position. [Subjects and Methods] The subjects of this study...
10.
Lee C, Kwak Y, Yang T, Han J, Park S, Ye M, et al.
Cell Rep
. 2016 Dec;
17(12):3219-3232.
PMID: 28009291
Myeloid-derived suppressor cells (MDSCs) are well known regulators of regulatory T cells (Treg cells); however, the direct regulation of MDSCs by Treg cells has not been well characterized. We find...