Woncheol Kim
Overview
Explore the profile of Woncheol Kim including associated specialties, affiliations and a list of published articles.
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13
Citations
156
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Recent Articles
1.
Kim S, Yun J, Kim W, Seon E, Lee C, Jeon J, et al.
Skin Res Technol
. 2024 Sep;
30(10):e70046.
PMID: 39331532
Introduction: Ceramides are essential epidermal constituents that play a critical role in skin moisturization treatment as a raw material in cosmetics formulation. Recently, ceramides have been known to be frequently...
2.
Shim T, Kim J, Kim W, Lee Y, Cho B, Moon C
iScience
. 2024 Feb;
27(2):108933.
PMID: 38318354
Neuritogenesis is crucial for establishing proper neuronal connections during brain development; its failure causes neurodevelopmental defects. Cullin-RING E3 ubiquitin ligase complexes participate in various neurodevelopmental processes by regulating protein stability....
3.
Haushalter R, Kim W, Chavkin T, The L, Garber M, Nhan M, et al.
Metab Eng
. 2014 Sep;
26:111-118.
PMID: 25250846
Microbial fermentation is emerging as an increasingly important resource for the production of fatty acids to serve as precursors for renewable diesel as well as detergents, lubricants and other industrial...
4.
Wang P, Kim W, Pickens L, Gao X, Tang Y
Angew Chem Int Ed Engl
. 2012 Oct;
51(44):11136-40.
PMID: 23024027
A very accommodating host: Three tetracycline biosynthetic pathways were overexpressed and manipulated in the heterologous host Streptomyces lividans K4-114. Through the inactivation of various genes and characterization of the resulting...
5.
Yuzawa S, Kim W, Katz L, Keasling J
Curr Opin Biotechnol
. 2012 Jan;
23(5):727-35.
PMID: 22244790
Heterologous production of polyketide compounds, an important class of natural products with complex chemical structures, was first demonstrated with Streptomyces parvulus in 1984. Although Streptomyces strains are good first options...
6.
Kim W, Lee J, Paik S, Hong Y
J Microbiol Biotechnol
. 2010 Dec;
20(11):1484-90.
PMID: 21124051
In the Streptomyces hygroscopicus JCM4427 geldanamycin biosynthetic gene cluster, Five putative regulatory genes were identified by protein homology searching. Among three of those genes, gel14, gel17, and gel19, are located...
7.
Pickens L, Kim W, Wang P, Zhou H, Watanabe K, Gomi S, et al.
J Am Chem Soc
. 2009 Nov;
131(48):17677-89.
PMID: 19908837
SF2575 1 is a tetracycline polyketide produced by Streptomyces sp. SF2575 and displays exceptionally potent anticancer activity toward a broad range of cancer cell lines. The structure of SF2575 is...
8.
Kim W, Lee D, Hong S, Na Z, Shin J, Roh S, et al.
Chembiochem
. 2009 Mar;
10(7):1243-51.
PMID: 19308924
Tailor made: We report the rational biosynthesis of C15 hydroxylated non-quinone geldanamycin analogues by site-directed mutagenesis of the geldanamycin polyketide synthase (PKS), together with a combination of post-PKS tailoring genes....
9.
Lee K, Ryu J, Jin Y, Kim W, Kaur N, Chung S, et al.
Org Biomol Chem
. 2008 Jan;
6(2):340-8.
PMID: 18175003
A new series of geldanamycin derivatives were synthesized using a semi-synthetic approach involving genetically engineered biosynthetic intermediates. These analogues were then evaluated for anti-proliferation activity in human cancer cell lines,...
10.
Kim W, Lee J, Lee D, Cai X, Shin J, Lee K, et al.
Chembiochem
. 2007 Jul;
8(13):1491-4.
PMID: 17661303
No abstract available.