Wolfgang Schaper
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Explore the profile of Wolfgang Schaper including associated specialties, affiliations and a list of published articles.
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97
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3541
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Recent Articles
1.
Kubin T, Gajawada P, Bramlage P, Hein S, Berge B, Cetinkaya A, et al.
Int J Mol Sci
. 2022 Feb;
23(3).
PMID: 35163735
Oncostatin M (OSM), a member of the interleukin-6 family, functions as a major mediator of cardiomyocyte remodeling under pathological conditions. Its involvement in a variety of human cardiac diseases such...
2.
Kubin T, Cetinkaya A, Kubin N, Bramlage P, Sen-Hild B, Gajawada P, et al.
Int J Mol Sci
. 2020 Sep;
21(17).
PMID: 32882982
Fetal and hypertrophic remodeling are hallmarks of cardiac restructuring leading chronically to heart failure. Since the Ras/Raf/MEK/ERK cascade (MAPK) is involved in the development of heart failure, we hypothesized, first,...
3.
Troidl K, Schubert C, Vlacil A, Chennupati R, Koch S, Schutt J, et al.
Cells
. 2020 Apr;
9(4).
PMID: 32316253
Beyond their role in pathogen recognition and the initiation of immune defense, Toll-like receptors (TLRs) are known to be involved in various vascular processes in health and disease. We investigated...
4.
Troidl K, Hammerschick T, Albarran-Juarez J, Jung G, Schierling W, Tonack S, et al.
Arterioscler Thromb Vasc Biol
. 2020 Mar;
40(5):e126-e137.
PMID: 32188276
Objective: Arteriogenesis, describing the process of collateral artery growth, is activated by fluid shear stress (FSS). Since this vascular mechanotransduction may involve microRNAs (miRNAs), we investigated the FSS-induced expression of...
5.
Guan Y, Cai B, Wu X, Peng S, Gan L, Huang D, et al.
Sci Rep
. 2017 Jul;
7(1):6643.
PMID: 28751690
Although collateral vessel growth is distinctly enhanced by elevated fluid shear stress (FSS), the underlying regulatory mechanism of this process remains incompletely understood. Recent studies have shown that microRNAs (miRNAs)...
6.
Guan Y, Cai B, Liu Z, Ye F, Deng P, Cai W, et al.
Cells Tissues Organs
. 2016 Jan;
201(2):118-29.
PMID: 26796132
We previously reported excessive growth of collateral vessels in the dog heart during arteriogenesis induced by implantation of an ameroid constrictor around the circumflex branch of the left coronary artery....
7.
Ito W, Lund N, Zhang Z, Buck F, Lellek H, Horst A, et al.
Biomed Res Int
. 2015 Jul;
2015:719316.
PMID: 26146628
Arteriogenesis is an inflammatory process associated with rapid cellular changes involving vascular resident endothelial progenitor cells (VR-EPCs). Extracellular cell surface bound 20S proteasome has been implicated to play an important...
8.
Yang B, Cai B, Deng P, Wu X, Guan Y, Zhang B, et al.
PLoS One
. 2015 Jul;
10(7):e0127931.
PMID: 26133549
Macrophage invasion is an important event during arteriogenesis, but the underlying mechanism is still only partially understood. The present study tested the hypothesis that nitric oxide (NO) and VE-cadherin, two...
9.
Actin-binding Rho activating protein is expressed in the central nervous system of normal adult rats
Liu L, Luo M, Yang B, Wu X, Zhu W, Guan Y, et al.
Neural Regen Res
. 2015 Feb;
7(13):965-70.
PMID: 25722683
Previous studies show that actin-binding Rho activating protein (Abra) is expressed in cardiomyocytes and vascular smooth muscle cells. In this study, we investigated the expression profile of Abra in the...
10.
Chandraratne S, von Bruehl M, Pagel J, Stark K, Kleinert E, Konrad I, et al.
Arterioscler Thromb Vasc Biol
. 2015 Jan;
35(3):589-97.
PMID: 25550202
Objective: Arteriogenesis is strongly dependent on the recruitment of leukocytes, especially monocytes, into the perivascular space of growing collateral vessels. On the basis of previous findings that platelets are central...