Wojciech Jawien
Overview
Explore the profile of Wojciech Jawien including associated specialties, affiliations and a list of published articles.
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23
Citations
70
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Recent Articles
1.
Florek E, Piekoszewski W, Czarnywojtek A, Sedziak A, Jawien W, Dera-Szymanowska A, et al.
Endokrynol Pol
. 2021 Dec;
73(1):16-25.
PMID: 34855194
Introduction: Tobacco smoke contains, among others, polycyclic aromatic hydrocarbons (PAHs), heterocyclic analogues, aromatic amines, N-nitrosamines, volatile hydrocarbons, aldehydes, phenols, miscellaneous organic compounds, metals, and inorganic compounds. Tobacco smoking can harm...
2.
Adamiak-Giera U, Jawien W, Pierzchlinska A, Bialecka M, Kobierski J, Janus T, et al.
Pharmaceutics
. 2021 Sep;
13(9).
PMID: 34575471
Parkinson's disease (PD) is a progressive, neurodegenerative disorder primarily affecting dopaminergic neuronal systems, with impaired motor function as a consequence. The most effective treatment for PD remains the administration of...
3.
Kotanska M, Kubacka M, Bednarski M, Nicosia N, Szafarz M, Jawien W, et al.
Pharmaceuticals (Basel)
. 2021 Aug;
14(8).
PMID: 34451896
GPR18 is an orphan GPCR that is activated by the cannabinoid tetrahydrocannabinol (THC). Emerging evidence indicates its involvement in the control of cardiovascular functions, including heart rate, contractility, vascular tone,...
4.
Kubacka M, Mogilski S, Zadrozna M, Nowak B, Szafarz M, Pomierny B, et al.
Pharmaceuticals (Basel)
. 2021 Jun;
14(5).
PMID: 34069933
Background: Quinazoline α-adrenoceptors antagonists have been shown to exert moderately favorable effects on the metabolic profile in hypertensive patients. However, based on AntiHypertensive and Lipid-Lowering Treatment to Prevent Heart Attack...
5.
Jawien W, Kobierski J
J Pharmacokinet Pharmacodyn
. 2020 Jan;
47(1):69-75.
PMID: 31900677
The lack in the literature of a simple, yet general and complete derivation of the widely used equation for non-compartmental calculation of steady-state volume of distribution is pointed out. It...
6.
Matyjaszczyk K, Kolonko M, Gonciarz-Dytman A, Oszczapowicz I, Lukawska M, Jawien W, et al.
J Chromatogr B Analyt Technol Biomed Life Sci
. 2017 Jun;
1060:44-52.
PMID: 28599260
The thermodynamic acid dissociation constants (pK and pK) of 16 anthracycline antibiotics, including doxorubicin (DOX) and daunorubicin (DAU), their epimers, epidoxorubicin (EDOX) and epidaunorubicin (EDAU), as well as novel anthracycline...
7.
Kus K, Kus E, Zakrzewska A, Jawien W, Sitek B, Walczak M, et al.
Pharmacol Rep
. 2017 Apr;
69(3):560-565.
PMID: 28364696
Purpose: To analyze the effect of liver steatosis and obesity on pharmacokinetic profile of two structurally-related liver-selective NO-donors - V-PYRRO/NO and V-PROLI/NO. Methods: C57BL/6 mice were fed control or high-fat...
8.
Jawien W, Wilimowska J, Klys M, Piekoszewski W
Pharmacol Rep
. 2017 Feb;
69(2):340-349.
PMID: 28187395
Background: Valproic acid (VPA) is a first-line antiepileptic drug. It is used in the treatment of many different types of partial and generalized epileptic seizures. Though the clinical pharmacokinetics of...
9.
Kasperek R, Zimmer L, Jawien W, Poleszak E
Acta Pol Pharm
. 2015 Dec;
72(3):527-38.
PMID: 26642661
Non-compartmental pharmacokinetic analysis of diclofenac sodium (DIC) and papaverine hydrochloride (PAP) after oral administration of composed tablets to rabbits was developed. HPLC method for determination of DIC and PAP in...
10.
Florek E, Kulza M, Piekoszewski W, Gomolka E, Jawien W, Tezyk A, et al.
Pharmacol Rep
. 2015 Sep;
67(5):921-7.
PMID: 26398386
Background: A vast majority of people who abuse alcohol are also defined as "heavy smokers". Tobacco smokes induces CYP1A1, CYP1A2, CYP2A6 isoenzymes, but on the other hand, ethanol activates CYP2E1,...