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Woan-Yu Lin

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Articles 12
Citations 644
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Recent Articles
1.
Liao Y, Gao I, Kusakabe T, Lin W, Grier A, Pan X, et al.
Nature . 2024 Nov; 636(8043):697-704. PMID: 39604728
The gut mycobiota is crucial for intestinal homeostasis and immune function. Yet its variability and inconsistent fungal colonization of laboratory mice hinders the study of the evolutionary and immune processes...
2.
Kusakabe T, Lin W, Cheong J, Singh G, Ravishankar A, Yeung S, et al.
Nat Immunol . 2023 Oct; 24(11):1879-1889. PMID: 37872315
Gastrointestinal fungal dysbiosis is a hallmark of several diseases marked by systemic immune activation. Whether persistent pathobiont colonization during immune alterations and impaired gut barrier function has a durable impact...
3.
Lin W, Iliev I
Science . 2023 Aug; 381(6657):483-484. PMID: 37535732
Specialized epithelium secretes an antifungal peptide.
4.
Iliev I, Lin W, Gaffen S
Cell . 2023 Feb; 186(3):466-468. PMID: 36736299
Microbiota-induced IL-17 production mediates CNS processes and animal behavior. However, its role on the peripheral nervous system (PNS) remains largely unknown. Enamorado et al. demonstrate that commensal-specific Th17 cells are...
5.
Li X, Leonardi I, Putzel G, Semon A, Fiers W, Kusakabe T, et al.
Nature . 2022 Jul; 608(7922):E21. PMID: 35859182
No abstract available.
6.
Li X, Leonardi I, Putzel G, Semon A, Fiers W, Kusakabe T, et al.
Nature . 2022 Mar; 603(7902):672-678. PMID: 35296857
The fungal microbiota (mycobiota) is an integral part of the complex multikingdom microbial community colonizing the mammalian gastrointestinal tract and has an important role in immune regulation. Although aberrant changes...
7.
Leonardi I, Gao I, Lin W, Allen M, Li X, Fiers W, et al.
Cell . 2022 Feb; 185(5):831-846.e14. PMID: 35176228
Fungal communities (the mycobiota) are an integral part of the gut microbiota, and the disruption of their integrity contributes to local and gut-distal pathologies. Yet, the mechanisms by which intestinal...
8.
Doron I, Mesko M, Li X, Kusakabe T, Leonardi I, Shaw D, et al.
Nat Microbiol . 2021 Nov; 6(12):1493-1504. PMID: 34811531
Secretory immunoglobulin A (sIgA) plays an important role in gut barrier protection by shaping the resident microbiota community, restricting the growth of bacterial pathogens and enhancing host protective immunity via...
9.
Doron I, Leonardi I, Li X, Fiers W, Semon A, Bialt-DeCelie M, et al.
Cell . 2021 Feb; 184(4):1017-1031.e14. PMID: 33548172
Antibodies mediate natural and vaccine-induced immunity against viral and bacterial pathogens, whereas fungi represent a widespread kingdom of pathogenic species for which neither vaccine nor neutralizing antibody therapies are clinically...
10.
Lee J, Hall J, Kroehling L, Wu L, Najar T, Nguyen H, et al.
Cell . 2020 Dec; 183(7):2036-2039. PMID: 33357400
No abstract available.