Wing-Kin Syn
Overview
Explore the profile of Wing-Kin Syn including associated specialties, affiliations and a list of published articles.
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Articles
128
Citations
3930
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Recent Articles
1.
Kaya E, Syn W, Manka P
Curr Opin Gastroenterol
. 2025 Feb;
PMID: 39998880
Purpose Of Review: Obesity and type 2 diabetes mellitus (T2DM) are significant global health challenges, closely linked to metabolic dysfunction-associated steatotic liver disease (MASLD). Glucagon-like peptide-1 receptor agonists (GLP-1RAs) have...
2.
Kilani Y, Alsakarneh S, Madi M, Mosquera D, Ferreira M, Jaber F, et al.
Aliment Pharmacol Ther
. 2024 Dec;
61(4):682-692.
PMID: 39660607
Background: Vitamin D deficiency is linked to worse outcomes in patients with chronic liver diseases (CLD). However, data in patients with autoimmune hepatitis (AIH) remain limited. Aims: We aimed to...
3.
Mahmoud M, Kawtharany H, Awali M, Mahmoud N, Mohamed I, Syn W
Clin Transl Gastroenterol
. 2024 Nov;
16(1):e00787.
PMID: 39503363
Introduction: Sex steroids modulate metabolic dysfunction-associated steatotic liver disease (MASLD) pathobiology. We hypothesized that testosterone treatment (TT) modulates progression of MASLD and performed a systematic review to evaluate the efficacy...
4.
Coombes J, Manka P, Swiderska-Syn M, Vannan D, Riva A, Claridge L, et al.
Liver Int
. 2024 Oct;
45(4):e16131.
PMID: 39422353
Background And Aims: Osteopontin (OPN) promotes the ductular reaction and is a major driver of chronic liver disease (CLD) progression. Although CLD is characterised by the accumulation of inflammatory cells...
5.
Zouridis S, Nasir A, Aspichueta P, Syn W
Digestion
. 2024 Oct;
:1-9.
PMID: 39369701
Background: Metabolic syndrome (MetS) is a cluster of cardiometabolic conditions that has been linked to high risk for cardiovascular disease, liver complications, and several malignancies. More recently, MetS has been...
6.
Mahmoud M, Nwankwo Jr E, Zhang Z, Matiwala N, Tripathi R, Mohamed I, et al.
Am J Med Sci
. 2024 Sep;
PMID: 39245183
Background: Although cystic fibrosis (CF) is widely considered a lung disease, the prevalence of CF-specific gastrointestinal symptoms and diseases has continued to rise. Peptic ulcer disease (PUD) has not been...
7.
Zouridis S, Oo Y, Syn W
ACG Case Rep J
. 2024 Jul;
11(7):e01414.
PMID: 38994192
Autoimmune hepatitis (AIH) is a rare chronic liver disease affecting annually 100,000-200,000 individuals in the United States. The first-line therapy in AIH is azathioprine and corticosteroids. However, adverse events may...
8.
Mahmoud M, Syn W
Dig Dis Sci
. 2024 Jun;
69(8):2741-2753.
PMID: 38864929
Purpose Of Review: The recent surge in inflammatory bowel disease (IBD) cases has paralleled a significant rise in obesity and metabolic comorbidities rates. In this article, we explore the potential...
9.
Manka P, Coombes J, Sydor S, Swiderska-Syn M, Best J, Gauthier K, et al.
Liver Int
. 2023 Oct;
44(1):125-138.
PMID: 37872645
Objective: Progressive hepatic fibrosis can be considered the final stage of chronic liver disease. Hepatic stellate cells (HSC) play a central role in liver fibrogenesis. Thyroid hormones (TH, e.g. thyroxine;...
10.
Nysather J, Kaya E, Manka P, Gudsoorkar P, Syn W
Adv Kidney Dis Health
. 2023 Sep;
30(4):315-335.
PMID: 37657879
Nonalcoholic fatty liver disease is a multisystem condition with effects beyond the liver. The identification of chronic kidney disease as an independent mediator of nonalcoholic fatty liver disease or associated...