Winfried Wiegraebe
Overview
Explore the profile of Winfried Wiegraebe including associated specialties, affiliations and a list of published articles.
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10
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1524
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Recent Articles
1.
Gregor B, Coston M, Adams E, Arakaki J, Borensztejn A, Do T, et al.
Nat Protoc
. 2023 Dec;
19(2):565-594.
PMID: 38087082
To produce abundant cell culture samples to generate large, standardized image datasets of human induced pluripotent stem (hiPS) cells, we developed an automated workflow on a Hamilton STAR liquid handler...
2.
Viana M, Chen J, Knijnenburg T, Vasan R, Yan C, Arakaki J, et al.
Nature
. 2023 Jan;
613(7943):345-354.
PMID: 36599983
Understanding how a subset of expressed genes dictates cellular phenotype is a considerable challenge owing to the large numbers of molecules involved, their combinatorics and the plethora of cellular behaviours...
3.
McQuin C, Goodman A, Chernyshev V, Kamentsky L, Cimini B, Karhohs K, et al.
PLoS Biol
. 2018 Jul;
16(7):e2005970.
PMID: 29969450
CellProfiler has enabled the scientific research community to create flexible, modular image analysis pipelines since its release in 2005. Here, we describe CellProfiler 3.0, a new version of the software...
4.
Ma L, Qiu Q, Gradwohl S, Scott A, Yu E, Alexander R, et al.
Proc Natl Acad Sci U S A
. 2012 Mar;
109(14):5481-6.
PMID: 22431605
In the mammalian brain, similar features of the sensory stimuli are often represented in proximity in the sensory areas. However, how chemical features are represented in the olfactory bulb has...
5.
Hao Y, Xu N, Box A, Schaefer L, Kannan K, Zhang Y, et al.
PLoS Genet
. 2011 May;
7(5):e1002065.
PMID: 21573134
Elevation of the second messenger cGMP by nitric oxide (NO) activates the cGMP-dependent protein kinase PKG, which is key in regulating cardiovascular, intestinal, and neuronal functions in mammals. The NO-cGMP-PKG...
6.
Gardner J, Smoyer C, Stensrud E, Alexander R, Gogol M, Wiegraebe W, et al.
J Cell Biol
. 2011 Apr;
193(3):489-507.
PMID: 21518795
Understanding the relationship between chromatin and proteins at the nuclear periphery, such as the conserved SUN family of inner nuclear membrane (INM) proteins, is necessary to elucidate how three-dimensional nuclear...
7.
Lutes A, Neaves W, Baumann D, Wiegraebe W, Baumann P
Nature
. 2010 Feb;
464(7286):283-6.
PMID: 20173738
Although bisexual reproduction has proven to be highly successful, parthenogenetic all-female populations occur frequently in certain taxa, including the whiptail lizards of the genus Aspidoscelis. Allozyme analysis revealed a high...
8.
Xie Y, Yin T, Wiegraebe W, He X, Miller D, Stark D, et al.
Nature
. 2008 Dec;
457(7225):97-101.
PMID: 19052548
Haematopoietic stem cell (HSC) niches, although proposed decades ago, have only recently been identified as separate osteoblastic and vascular microenvironments. Their interrelationships and interactions with HSCs in vivo remain largely...
9.
SAM domain-based protein oligomerization observed by live-cell fluorescence fluctuation spectroscopy
Slaughter B, Huff J, Wiegraebe W, Schwartz J, Li R
PLoS One
. 2008 Apr;
3(4):e1931.
PMID: 18431466
Sterile-alpha-motif (SAM) domains are common protein interaction motifs observed in organisms as diverse as yeast and human. They play a role in protein homo- and hetero-interactions in processes ranging from...
10.
Aulehla A, Wiegraebe W, Baubet V, Wahl M, Deng C, Taketo M, et al.
Nat Cell Biol
. 2007 Dec;
10(2):186-93.
PMID: 18157121
Rhythmic production of vertebral precursors, the somites, causes bilateral columns of embryonic segments to form. This process involves a molecular oscillator--the segmentation clock--whose signal is translated into a spatial, periodic...