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Wim Van Paesschen

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Articles 136
Citations 1677
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Recent Articles
1.
Zhang J, Liu Z, Chatzichristos C, Michiels S, Van Paesschen W, Hughes D, et al.
J Neural Eng . 2025 Mar; PMID: 40064111
Tonic-clonic seizures (TCSs), which present a significant risk for sudden unexpected death in epilepsy (SUDEP), require accurate detection to enable effective long-term monitoring. Previous studies have demonstrated the advantages of...
2.
Devulder A, Vanderlinden G, Cleeren E, Goovaerts V, Theys T, Van Laere K, et al.
BMC Neurol . 2024 Dec; 24(1):478. PMID: 39696024
Background: Neuronal hyperexcitability has been proposed to play a key role in Alzheimer's disease (AD). Understanding the relation between this enhanced excitability and AD pathology could provide a window for...
3.
Ramirez J, Vanhoyland M, Ratan Murty N, Decramer T, Van Paesschen W, Bracci S, et al.
Proc Natl Acad Sci U S A . 2024 Dec; 121(51):e2408871121. PMID: 39652751
Body perception plays a fundamental role in social cognition. Yet, the neural mechanisms underlying this process in humans remain elusive given the spatiotemporal constraints of functional imaging. Here, we present...
4.
Kraft F, Rodriguez-Aliaga P, Yuan W, Franken L, Zajt K, Hasan D, et al.
Science . 2024 Oct; 386(6721):516-525. PMID: 39480921
Malformations of the brain are common and vary in severity, from negligible to potentially fatal. Their causes have not been fully elucidated. Here, we report pathogenic variants in the core...
5.
Proost R, Cleeren E, Jansen B, Lagae L, Van Paesschen W, Jansen K
Epilepsia . 2024 Sep; 65(11):3335-3349. PMID: 39254374
Objective: We aimed to investigate sleep in children with drug-resistant epilepsy (DRE), including developmental and epileptic encephalopathies (DEEs). Next, we examined differences in sleep macrostructure and microstructure and questionnaire outcomes...
6.
Devulder A, Vanderlinden G, van Langenhoven L, Testelmans D, Van Den Bossche M, De Winter F, et al.
Brain . 2024 Jul; 148(2):506-520. PMID: 38990981
Both sleep alterations and epileptiform activity are associated with the accumulation of amyloid-β and tau pathology and are currently investigated for potential therapeutic interventions in Alzheimer's disease. However, a bidirectional...
7.
Zabler N, Swinnen L, Biondi A, Novitskaya Y, Schutz E, Epitashvili N, et al.
Sci Rep . 2024 Jul; 14(1):15823. PMID: 38982283
People with epilepsy frequently under- or inaccurately report their seizures, which poses a challenge for evaluating their treatment. The introduction of epilepsy health apps provides a novel approach that could...
8.
Macea J, Swinnen L, Varon C, De Vos M, Van Paesschen W
Epilepsy Behav . 2024 Jun; 158:109917. PMID: 38924968
Purpose: Seizures are characterized by periictal autonomic changes. Wearable devices could help improve our understanding of these phenomena through long-term monitoring. In this study, we used wearable electrocardiogram (ECG) data...
9.
Smeijers S, Brems H, Verhaeghe A, Van Paesschen W, van Loon J, Van der Auweraer S, et al.
J Med Genet . 2024 Jun; 61(9):904-907. PMID: 38825366
Encephalocraniocutaneous lipomatosis (ECCL) is a sporadic congenital condition characterised by ocular, cutaneous and central nervous system involvement. Mosaic activating variants in and have been reported in several individuals with this...
10.
Bougou V, Vanhoyland M, Bertrand A, Van Paesschen W, Op de Beeck H, Janssen P, et al.
Nat Commun . 2024 May; 15(1):4608. PMID: 38816391
Object recognition and categorization are essential cognitive processes which engage considerable neural resources in the human ventral visual stream. However, the tuning properties of human ventral stream neurons for object...