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Wim H J Kruit

Explore the profile of Wim H J Kruit including associated specialties, affiliations and a list of published articles. Areas
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Articles 29
Citations 1340
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Recent Articles
1.
Leeneman B, Blommestein H, Coupe V, Hendriks M, Kruit W, Plaisier P, et al.
Melanoma Res . 2021 Apr; 31(3):249-257. PMID: 33871398
The aim of this study was to provide insight into real-world healthcare costs of patients initially diagnosed with localized or regionally advanced melanoma in three Dutch hospitals between 2003 and...
2.
Jochems A, van der Kooij M, Fiocco M, Schouwenburg M, Aarts M, van Akkooi A, et al.
Cancers (Basel) . 2019 Jul; 11(7). PMID: 31323802
Uveal melanoma (UM) is the most common primary intraocular tumor in adults. Up to 50% of UM patients will develop metastases. We present data of 175 metastatic UM patients diagnosed...
3.
Dreno B, Thompson J, Smithers B, Santinami M, Jouary T, Gutzmer R, et al.
Lancet Oncol . 2018 Jun; 19(7):916-929. PMID: 29908991
Background: Despite newly approved treatments, metastatic melanoma remains a life-threatening condition. We aimed to evaluate the efficacy of the MAGE-A3 immunotherapeutic in patients with stage IIIB or IIIC melanoma in...
4.
Jochems A, Leeneman B, Franken M, Schouwenburg M, Aarts M, van Akkooi A, et al.
Anticancer Drugs . 2018 Apr; 29(6):572-578. PMID: 29659371
Phase III trials with ipilimumab showed an improved survival in patients with metastatic melanoma. We evaluated the use and safety of ipilimumab, and the survival of all patients with metastatic...
5.
Franken M, Leeneman B, Jochems A, Schouwenburg M, Aarts M, van Akkooi A, et al.
Anticancer Drugs . 2018 Apr; 29(6):579-588. PMID: 29634490
There is limited evidence on the costs associated with ipilimumab. We investigated healthcare costs of all Dutch patients with advanced cutaneous melanoma who were treated with ipilimumab. Data were retrieved...
6.
van Dijk E, Kruit W, Jager M, Luyten G, Vingerling J, Boon C
Acta Ophthalmol . 2018 Jan; 96(7):712-718. PMID: 29338133
Purpose: To analyse ophthalmological adverse events associated with mitogen-activated protein kinase kinase (MEK) inhibition with pimasertib treatment for metastatic cutaneous melanoma (CM). Methods: In this prospective observational, cohort-based, cross-sectional study,...
7.
Kloth J, Hamberg P, Mendelaar P, Dulfer R, van der Holt B, Eechoute K, et al.
Eur J Cancer . 2016 Feb; 56:101-106. PMID: 26841094
Aim Of The Study: As a rise in mean corpuscular volume (MCV) of the erythrocyte is frequently seen during treatment with imatinib and sunitinib, we investigated whether macrocytosis (MCV > ...
8.
Kruit W, Suciu S, Dreno B, Mortier L, Robert C, Chiarion-Sileni V, et al.
J Clin Oncol . 2013 May; 31(19):2413-20. PMID: 23715572
Purpose: Active immunization against the tumor-specific MAGE-A3 antigen is followed by a few but impressive and durable clinical responses. This randomized phase II trial evaluated two different immunostimulants combined with...
9.
Ulloa-Montoya F, Louahed J, Dizier B, Gruselle O, Spiessens B, Lehmann F, et al.
J Clin Oncol . 2013 May; 31(19):2388-95. PMID: 23715562
Purpose: To detect a pretreatment gene expression signature (GS) predictive of response to MAGE-A3 immunotherapeutic in patients with metastatic melanoma and to investigate its applicability in a different cancer setting...
10.
Busse A, Rapion J, Fusi A, Suciu S, Nonnenmacher A, Santinami M, et al.
Cancer Immunol Immunother . 2013 Apr; 62(7):1223-33. PMID: 23624802
We analysed mRNA levels of interferon response genes (ISG15, STAT1, CXCL10) of inhibitors of the JAK/STAT pathway (STAT3, SOCS1, SOCS3) and of cytokines (TNFα, IL10, TGFß1) in peripheral blood of...