Willias Masocha
Overview
Explore the profile of Willias Masocha including associated specialties, affiliations and a list of published articles.
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Articles
56
Citations
767
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Recent Articles
1.
Al-Romaiyan A, Barakat A, Marafie S, Masocha W
Front Pharmacol
. 2024 Oct;
15:1478917.
PMID: 39399466
Background: For ages, botanical medicine has been used in the treatment of diabetes mellitus (DM). Notoginsenoside R1 (NGR1), a Panax notoginseng (Burkill) F.H.Chen metabolite, has been documented to possess antidiabetic...
2.
Masocha W, Aly E, Albaloushi A, Al-Romaiyan A
Biomedicines
. 2024 Jul;
12(7).
PMID: 39062118
The use of paclitaxel as a chemotherapeutic drug is limited by the development of dose-dependent paclitaxel-induced neuropathic pain (PINP). Recently, we observed that the combination of indomethacin plus minocycline (IPM)...
3.
Al-Romaiyan A, Barakat A, Jose L, Masocha W
Front Pharmacol
. 2024 Jan;
14:1295096.
PMID: 38186647
Chemotherapy-induced neuropathic pain (CINP) is a debilitating side effect in individuals undergoing cancer treatment. Treatment of CINP with the current available classes of drugs is limited and often yields unsatisfactory...
4.
Shayea A, Renno W, Qabazard B, Masocha W
Int J Mol Sci
. 2023 Dec;
24(23).
PMID: 38068971
Diabetic neuropathy is an important long-term complication of diabetes. This study explored the hypothesis that hydrogen sulfide (HS) ameliorates neuropathic pain by controlling antiapoptotic and pro-apoptotic processes. The effects of...
5.
Khajah M, Hawai S, Barakat A, Albaloushi A, Alkharji M, Masocha W
Front Pharmacol
. 2023 Nov;
14:1252174.
PMID: 38034999
A few studies have highlighted the anti-inflammatory properties of minocycline in reducing colitis severity in mice, but its molecular mechanism is not fully understood. The aim of this study was...
6.
Munawar N, Bitar M, Masocha W
Int J Mol Sci
. 2023 Sep;
24(18).
PMID: 37762636
Neuropathic pain is a well-documented phenomenon in experimental and clinical diabetes; however, current treatment is unsatisfactory. Serotoninergic-containing neurons are key components of the descending autoinhibitory pathway, and a decrease in...
7.
Alhadlaq M, Masocha W
Int J Mol Sci
. 2023 Aug;
24(16).
PMID: 37628987
Microglia activation in the spinal cord play a major role in the pathogenesis of neuropathic pain. The p38 mitogen-activated protein kinase (MAPK) regulates microglia activation. Previously, 2',3'-dideoxycytidine (ddC), a nucleoside...
8.
Jarragh A, Shuaib A, Al-Khaledi G, Alotaibi F, Al-Sabah S, Masocha W
Transl Neurosci
. 2023 May;
14(1):20220287.
PMID: 37250141
Objective: The main objective of this study is to design a custom-made weight-drop impactor device to produce a consistent spinal cord contusion model in rats in order to examine the...
9.
Masocha W, Idro R, Furlan R, Lakhdar-Ghazal N
Front Immunol
. 2023 May;
14:1201494.
PMID: 37207225
No abstract available.
10.
Al-HadlaQ M, Masocha W
Biomedicines
. 2023 Mar;
11(3).
PMID: 36979854
Nucleoside reverse transcriptase inhibitors (NRTIs), drugs used to treat HIV infection, can cause neuropathic pain (NP) and neuroinflammation. An NRTI, 2'-3'-dideoxycytidine (ddC), was reported to induce mechanical allodynia and increase...