William Shanthakumar Thulasitha
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Explore the profile of William Shanthakumar Thulasitha including associated specialties, affiliations and a list of published articles.
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16
Citations
38
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Recent Articles
1.
Umasuthan N, Bathige S, Thulasitha W, Oh M, Lee J
Biomolecules
. 2020 Oct;
10(10).
PMID: 32998424
CXCL8 (interleukin-8, IL-8) is a CXC family chemokine that recruits specific target cells and mediates inflammation and wound healing. This study reports the identification and characterization of two homologs from...
2.
Bathige S, Umasuthan N, Godahewa G, Thulasitha W, Jayasinghe J, Wan Q, et al.
Fish Shellfish Immunol
. 2017 Aug;
69:128-141.
PMID: 28818616
Signal transducers and activators of transcription 1 (STAT1) is critically involved in mediating cytokine-driven signaling, and triggers the transcription of target genes to activate cellular functions. Although the structural and...
3.
Bathige S, Umasuthan N, Priyathilaka T, Thulasitha W, Jayasinghe J, Wan Q, et al.
Gene
. 2017 May;
626:95-105.
PMID: 28499943
Signal transducer and activator of transcription 2 (STAT2) is a key element that transduces signals from the cell membrane to the nucleus via the type I interferon-signaling pathway. Although the...
4.
Bathige S, Thulasitha W, Umasuthan N, Jayasinghe J, Wan Q, Nam B, et al.
Vet Immunol Immunopathol
. 2017 Apr;
186:29-40.
PMID: 28413047
Signal transducer and activator of transcription 3 (STAT3) is one of the crucial transcription factors in the Janus kinase (JAK)/STAT signaling pathway, and it was previously considered as acute phase...
5.
Thulasitha W, Umasuthan N, Wan Q, Nam B, Kang T, Lee J
Dev Comp Immunol
. 2017 Jan;
71:70-81.
PMID: 28131766
A β-galactoside binding lectin, designated as galectin-2, was identified and characterized from rock bream Oplegnathus fasciatus (OfGal-2). The cDNA of OfGal-2 comprised of 692 bp with a coding sequence of...
6.
Umasuthan N, Bathige S, Thulasitha W, Jayasooriya R, Shin Y, Lee J
Fish Shellfish Immunol
. 2017 Jan;
62:276-290.
PMID: 28111358
Toll-like receptor 5 (TLR5) recognizes bacterial flagellin and induces the downstream signaling through the myeloid differentiation primary response gene 88 (MyD88) protein to produce proinflammatory cytokines. In this study, we...
7.
Kugapreethan R, Umasuthan N, Wan Q, Thulasitha W, Kim C, Lee J
Dev Comp Immunol
. 2016 Dec;
67:43-56.
PMID: 27984102
Elevated levels of ROS can cause serious intracellular damages by reacting readily with nucleic acids, proteins and lipids, thus triggering tissue damage and cell death. Thioredoxin system is one of...
8.
Thulasitha W, Kim Y, Umasuthan N, Jayasooriya R, Kim G, Nam B, et al.
Fish Shellfish Immunol
. 2016 Mar;
54:11-21.
PMID: 27026037
Thioredoxin domain-containing protein 12 (TXNDC12) is a small, disulfide-containing protein that belongs to the thioredoxin (TXN) superfamily. In the present study, we identified and characterized a TXNDC12-like gene, designated OfTXNDC12,...
9.
Thulasitha W, Umasuthan N, Jayasooriya R, Noh J, Park H, Lee J
Comp Biochem Physiol C Toxicol Pharmacol
. 2016 Mar;
185-186:29-37.
PMID: 26945103
Thioredoxin (TXN) superfamily proteins are identified by the presence of a thioredoxin active site with a conserved CXXC active motif. TXN members are involved in a wide range of biochemical...
10.
Thulasitha W, Umasuthan N, Whang I, Nam B, Lee J
Fish Shellfish Immunol
. 2016 Jan;
50:66-78.
PMID: 26792759
In this study, we describe the identification and characterization of a proto type galectin, galectin-1, from rock bream Oplegnathus fasciatus (OfGal-1). Galectins are evolutionarily conserved carbohydrate binding lectins that show...