William R Watson
Overview
Explore the profile of William R Watson including associated specialties, affiliations and a list of published articles.
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14
Citations
151
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Recent Articles
1.
Sweetman D, Strickland T, Melo A, Kelly L, Onwuneme C, Watson W, et al.
Front Pediatr
. 2021 Feb;
8:556216.
PMID: 33628760
To investigate the relationship between cytokines associated with innate immune cell activation and brain injury and outcome in infants with NE compared to neonatal controls. Serum and CSF biomarkers associated...
2.
Janakiraman S, Watson S, Watson W
TechTrends
. 2021 Feb;
65(3):331-347.
PMID: 33521794
Environmental sustainability education should create eco-awareness and produce pro-environmental behaviors. Traditional instructional methods create eco-awareness but do not make people act. Purposefully designed digital games for attitudinal instruction provide cognitive...
3.
Drapela S, Khirsariya P, van Weerden W, Fedr R, Suchankova T, Buzova D, et al.
Mol Oncol
. 2020 Jun;
14(10):2487-2503.
PMID: 32579780
As treatment options for patients with incurable metastatic castration-resistant prostate cancer (mCRPC) are considerably limited, novel effective therapeutic options are needed. Checkpoint kinase 1 (CHK1) is a highly conserved protein...
4.
Eustace A, Conlon N, McDermott M, Browne B, OLeary P, Holmes F, et al.
BMC Cancer
. 2018 Oct;
18(1):965.
PMID: 30305055
Background: Lapatinib has clinical efficacy in the treatment of trastuzumab-refractory HER2-positive breast cancer. However, a significant proportion of patients develop progressive disease due to acquired resistance to the drug. Induction...
5.
Sweetman D, Onwuneme C, Watson W, Murphy J, Molloy E
Neonatology
. 2016 Dec;
111(3):253-259.
PMID: 27902983
Background: Infants with neonatal encephalopathy (NE) of hypoxic-ischaemic origin are at risk of oxidative and ischaemia-reperfusion injury, which may induce abnormal inflammatory responses involving excessive cytokine production and release in...
6.
Sweetman D, Onwuneme C, Watson W, ONeill A, Murphy J, Molloy E
Acta Paediatr
. 2016 Aug;
105(11):e513-e519.
PMID: 27551944
Aim: Perinatal asphyxia is associated with multi-organ injury including acute kidney injury (AKI). New urinary biomarkers may detect more subtle renal injury. Methods: Urinary biomarkers (albumin, beta-2 microglobulin, cystatin-C, epidermal...
7.
Johnson I, Parkinson-Lawrence E, Keegan H, Spillane C, Barry-OCrowley J, Watson W, et al.
Oncotarget
. 2015 Oct;
6(35):37919-29.
PMID: 26473288
Prostate cancer continues to be a major cause of morbidity and mortality in men, but a method for accurate prognosis in these patients is yet to be developed. The recent...
8.
Fitzgerald K, Evans J, McCarthy J, Guo J, Prencipe M, Kearney M, et al.
Expert Opin Ther Targets
. 2014 Mar;
18(6):633-49.
PMID: 24660778
Introduction: Prostate cancer is a leading cause of cancer-related death in men and current treatments offer only a modest survival benefit in advanced stages of the disease. RNA interference (RNAi)...
9.
Prencipe M, Madden S, ONeill A, OHurley G, Culhane A, OConnor D, et al.
Prostate
. 2013 Jan;
73(7):743-53.
PMID: 23359479
Background: Advanced prostate cancer is treated by hormone ablation therapy. However, despite an initial response, the majority of men relapse to develop castration-resistant disease for which there are no effective...
10.
Soo A, Maher B, Daly L, Wood A, Watson W
Interact Cardiovasc Thorac Surg
. 2010 Aug;
11(5):604-11.
PMID: 20724426
Objectives: Open heart surgery is associated with a massive systemic inflammatory response. Neutrophils, are the main mediator of this response. We hypothesised that the degree of neutrophil activation and inflammatory...