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William M Shih

Explore the profile of William M Shih including associated specialties, affiliations and a list of published articles. Areas
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Articles 69
Citations 4818
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Recent Articles
1.
Lee J, Kim J, Posnjak G, Ershova A, Hayakawa D, Shih W, et al.
Nano Lett . 2024 Dec; 25(1):16-27. PMID: 39704025
Over the last three decades, colloidal crystallization has provided an easy-to-craft platform for mesoscale engineering of photonic and phononic crystals. Nevertheless, the crystal lattices achieved thus far with commodity colloids...
2.
Young O, Dembele H, Rajwar A, Kwon I, Ryu J, Shih W, et al.
Small Methods . 2024 Dec; :e2401376. PMID: 39651835
In recent years, notable advances in nanotechnology-based drug delivery have emerged. A particularly promising platform in this field is DNA origami-based nanoparticles, which offer highly programmable surfaces, providing precise control...
3.
Young O, Dembele H, Rajwar A, Kwon I, Ryu J, Shih W, et al.
bioRxiv . 2024 Sep; PMID: 39253502
In recent years, notable advances in nanotechnology-based drug delivery have emerged. A particularly promising platform in this field is DNA origami-based nanoparticles, which offer highly programmable surfaces, providing precise control...
4.
Deng J, Minev D, Ershova A, Shih W
J Am Chem Soc . 2024 Mar; 146(13):9216-9223. PMID: 38529625
Controlling where and when self-assembly happens is crucial in both biological and synthetic systems as it optimizes the utilization of available resources. We previously reported strictly seed-initiated linear crisscross polymerization...
5.
Zeng Y, Young O, Wintersinger C, Anastassacos F, MacDonald J, Isinelli G, et al.
Nat Nanotechnol . 2024 Mar; 19(7):1055-1065. PMID: 38491184
Multivalent presentation of ligands often enhances receptor activation and downstream signalling. DNA origami offers a precise nanoscale spacing of ligands, a potentially useful feature for therapeutic nanoparticles. Here we use...
6.
Zeng Y, Young O, Si L, Ku M, Isinelli G, Rajwar A, et al.
bioRxiv . 2024 Jan; PMID: 38260393
Current SARS-CoV-2 vaccines have demonstrated robust induction of neutralizing antibodies and CD4 T cell activation, however CD8 responses are variable, and the duration of immunity and protection against variants are...
7.
Ershova A, Minev D, Corea-Dilbert F, Yu D, Deng J, Fontana W, et al.
J Am Chem Soc . 2023 Dec; 146(1):218-227. PMID: 38133996
The self-assembly of DNA-based monomers into higher-order structures has significant potential for realizing various biomimetic behaviors including algorithmic assembly, ultrasensitive detection, and self-replication. For these behaviors, it is desirable to...
8.
Kilwing L, Lill P, Nathwani B, Guerra R, Benson E, Liedl T, et al.
ACS Nano . 2023 Dec; 18(1):885-893. PMID: 38109901
DNA origami is a popular nanofabrication strategy that employs self-assembly of a long single scaffold strand, typically less than 10 kilobases in length, with hundreds of shorter staple strands into...
9.
Shrestha P, Yang D, Ward A, Shih W, Wong W
J Am Chem Soc . 2023 Dec; 145(51):27916-27921. PMID: 38096567
The ability to accurately map the 3D geometry of single-molecule complexes in trace samples is a challenging goal that would lead to new insights into molecular mechanics and provide an...
10.
Shrestha P, Yang D, Shih W, Wong W
bioRxiv . 2023 Jul; PMID: 37502860
The ability to accurately map the 3D geometry of single-molecule complexes in trace samples would lead to new insights into molecular mechanics and provide an approach for single-molecule structural proteomics....