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William L Wishart

Explore the profile of William L Wishart including associated specialties, affiliations and a list of published articles. Areas
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Citations 93
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Recent Articles
1.
Boos J, Kirk D, Piccolotto M, Zuercher W, Gfeller S, Neuner P, et al.
Nucleic Acids Res . 2013 Jun; 41(15):e145. PMID: 23766292
Efficient tissue-specific delivery is a crucial factor in the successful development of therapeutic oligonucleotides. Screening for novel delivery methods with unique tissue-homing properties requires a rapid, sensitive, flexible and unbiased...
2.
Mullershausen F, Craveiro L, Shin Y, Cortes-Cros M, Bassilana F, Osinde M, et al.
J Neurochem . 2007 May; 102(4):1151-61. PMID: 17488279
Sphingosine-1-phosphate (S1P) receptors are widely expressed in the central nervous system where they are thought to regulate glia cell function. The phosphorylated version of fingolimod/FTY720 (FTY720P) is active on a...
3.
Dorn G, Hall J, Husken D, Lange J, Martin P, Natt F, et al.
Nucleosides Nucleotides Nucleic Acids . 2003 Oct; 22(5-8):641-4. PMID: 14565243
Functional genomics is inundating the pharmaceutical industry with large numbers of potential gene targets from several sources such as gene expression profiling experiments (DNA microchips, proteomics) or database mining. Oligonucleotide-based...
4.
Hemmings-Mieszczak M, Dorn G, Natt F, Hall J, Wishart W
Nucleic Acids Res . 2003 Apr; 31(8):2117-26. PMID: 12682362
Synthetic 21-bp-long short interfering RNAs (siRNA) can stimulate sequence-specific mRNA degradation in mammalian cell cultures, a process referred to as RNA interference (RNAi). In the present study, the potential of...