William K C Cheung
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Explore the profile of William K C Cheung including associated specialties, affiliations and a list of published articles.
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12
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644
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Recent Articles
1.
Zhang W, Duan R, Zhang J, Cheung W, Gao X, Zhang R, et al.
Br J Cancer
. 2018 Jan;
118(4):522-533.
PMID: 29348487
Background: The therapeutic resistance to ionising radiation (IR) and anti-angiogenesis mainly impair the prognosis of patients with glioblastoma. The primary and secondary MET aberrant activation is one crucial factor for...
2.
Stevens L, Cheung W, Adua S, Arnal-Estape A, Zhao M, Liu Z, et al.
Cancer Res
. 2017 Feb;
77(8):1905-1917.
PMID: 28196904
Mechanisms underlying the propensity of latent lung adenocarcinoma (LUAD) to relapse are poorly understood. In this study, we show how differential expression of a network of extracellular matrix (ECM) molecules...
3.
Cao J, Wu L, Zhang S, Lu M, Cheung W, Cai W, et al.
Nucleic Acids Res
. 2016 Jul;
44(19):e149.
PMID: 27458201
The CRISPR/Cas9 system is a powerful genome editing tool and has been widely used for biomedical research. However, many challenges, such as off-target effects and lack of easy solutions for...
4.
Cao J, Liu Z, Cheung W, Zhao M, Chen S, Chan S, et al.
Cell Rep
. 2014 Mar;
6(5):868-77.
PMID: 24582965
Metastasis is a major clinical challenge for cancer treatment. Emerging evidence suggests that aberrant epigenetic modifications contribute significantly to tumor formation and progression. However, the drivers and roles of such...
5.
Cheung W, Zhao M, Liu Z, Stevens L, Cao P, Fang J, et al.
Cancer Cell
. 2013 May;
23(6):725-38.
PMID: 23707782
Molecular programs that mediate normal cell differentiation are required for oncogenesis and tumor cell survival in certain cancers. How cell-lineage-restricted genes specifically influence metastasis is poorly defined. In lung cancers,...
6.
Xia H, Cheung W, Ng S, Jiang X, Jiang S, Sze J, et al.
J Biol Chem
. 2012 Jan;
287(13):9962-9971.
PMID: 22253443
miR-124 is a brain-enriched microRNA that plays a crucial role in neural development and has been shown to be down-regulated in glioma and medulloblastoma, suggesting its possible involvement in brain...
7.
Cao P, Cheung W, Nguyen D
Discov Med
. 2011 Oct;
12(65):329-40.
PMID: 22031670
Cancer has long been compared to the aberrant development of human tissues. It was in the mid-19th century writings of Rudolf Virchow and Joseph Recamier that malignant tissue was first...
8.
Lin S, Cheung W, Chen S, Lu G, Wang Z, Xie D, et al.
Comput Biol Chem
. 2010 Sep;
34(4):232-41.
PMID: 20863765
A number of microRNAs (miRNAs) that are evolutionarily conserved not beyond primate lineage have been identified. These primate-specific miRNAs (ps-miRNAs) may attribute to the difference between high-level primates and non-primate...
9.
Xia H, Cheung W, Sze J, Lu G, Jiang S, Yao H, et al.
J Biol Chem
. 2010 Sep;
285(47):36995-7004.
PMID: 20826811
The emerging concept of generating cancer stem cells from epithelial-mesenchymal transition has attracted great interest; however, the factors and molecular mechanisms that govern this putative tumor-initiating process remain largely elusive....
10.
Cheung W, Yang P, Huang Q, Chen Z, Chen S, Lin M, et al.
Biochem Biophys Res Commun
. 2010 Feb;
394(1):18-23.
PMID: 20167204
Makorin-2, consisting of four highly conserved C(3)H zinc fingers, a Cys-His motif and a C(3)HC(4) RING zinc finger domain, is a putative ribonucleoprotein. We have previously reported that Xenopus makorin-2...