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William J Moorhead 3rd

Explore the profile of William J Moorhead 3rd including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Cuevas R, Hortells L, Chu C, Wong R, Crane A, Boufford C, et al.
Circ Res . 2025 Jan; 136(4):403-421. PMID: 39835393
Background: Calcific aortic valve disease is the pathological remodeling of valve leaflets. The initial steps in valve leaflet osteogenic reprogramming are not fully understood. As TERT (telomerase reverse transcriptase) overexpression...
2.
Behzadi P, Cuevas R, Crane A, Wendling A, Chu C, Moorhead 3rd W, et al.
bioRxiv . 2024 Aug; PMID: 39149364
Peripheral artery disease (PAD) is the narrowing of the arteries that carry blood to the lower extremities. PAD has been traditionally associated with atherosclerosis. However, recent studies have found that...
3.
Cuevas R, Wong R, Joolharzadeh P, Moorhead 3rd W, Chu C, Callahan 4th J, et al.
Am J Physiol Cell Physiol . 2022 Dec; 324(2):C327-C338. PMID: 36503240
Arterial calcification due to deficiency of CD73 (ACDC) is a rare genetic disease caused by a loss-of-function mutation in the gene encoding the ecto-5'-nucleotidase (cluster of differentiation 73, CD73) enzyme....
4.
Cuevas R, Chu C, Moorhead 3rd W, Wong R, Sultan I, St Hilaire C
J Vis Exp . 2021 May; (170). PMID: 33938898
Calcific aortic valve disease (CAVD) is present in nearly a third of the elderly population. Thickening, stiffening, and calcification of the aortic valve causes aortic stenosis and contributes to heart...
5.
Moorhead 3rd W, Chu C, Cuevas R, Callahan 4th J, Wong R, Regan C, et al.
Arterioscler Thromb Vasc Biol . 2020 May; 40(7):1680-1694. PMID: 32375544
Objective: The recessive disease arterial calcification due to deficiency of CD73 (ACDC) presents with extensive nonatherosclerotic medial layer calcification in lower extremity arteries. Lack of CD73 induces a concomitant increase...