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William J Honnen

Explore the profile of William J Honnen including associated specialties, affiliations and a list of published articles. Areas
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Articles 12
Citations 635
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Recent Articles
1.
Magni R, Rruga F, Alsaab F, Sharif S, Howard M, Espina V, et al.
Sci Rep . 2021 Sep; 11(1):19546. PMID: 34580341
No abstract available.
2.
Horton D, Barrett E, Roy J, Gennaro M, Andrews T, Greenberg P, et al.
J Infect Dis . 2021 Aug; 224(8):1345-1356. PMID: 34387310
Background: We studied risk factors, antibodies, and symptoms of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in a diverse, ambulatory population. Methods: A prospective cohort (n = 831) previously...
3.
Magni R, Rruga F, Alsaab F, Sharif S, Howard M, Espina V, et al.
Sci Rep . 2020 Aug; 10(1):13944. PMID: 32811861
An accurate urine test for diverse populations with active tuberculosis could be transformative for preventing TB deaths. Urinary liporabinomannan (LAM) testing has been previously restricted to HIV co-infected TB patients....
4.
Sigal G, Pinter A, Lowary T, Kawasaki M, Li A, Mathew A, et al.
J Clin Microbiol . 2018 Sep; 56(12). PMID: 30257899
The only currently commercialized point-of-care assay for tuberculosis (TB) that measures lipoarabinomannan (LAM) in urine (Alere LF-LAM) has insufficient sensitivity. We evaluated the potential of 100 novel monoclonal antibody pairs...
5.
Amin A, De P, Spencer J, Brennan P, Daum J, Andre B, et al.
Tuberculosis (Edinb) . 2018 Jul; 111:178-187. PMID: 30029905
TB diagnosis and treatment monitoring in resource limited regions rely heavily on serial sputum smear microscopy and bacterial culture. These microbiological methods are time-consuming, expensive and lack adequate sensitivity. The...
6.
Krachmarov C, Lai Z, Honnen W, Salomon A, Gorny M, Zolla-Pazner S, et al.
J Virol . 2011 Aug; 85(20):10730-40. PMID: 21835798
A series of potently neutralizing monoclonal antibodies (MAbs) that target quaternary epitopes on the native Env trimer have recently been described. A common feature shared by these antibodies is the...
7.
Moore P, Gray E, Sheward D, Madiga M, Ranchobe N, Lai Z, et al.
J Virol . 2011 Jan; 85(7):3128-41. PMID: 21270156
The targets of broadly cross-neutralizing (BCN) antibodies are of great interest in the HIV vaccine field. We have identified a subtype C HIV-1-superinfected individual, CAP256, with high-level BCN activity, and...
8.
Pinter A, Honnen W, DAgostino P, Gorny M, Zolla-Pazner S, Kayman S
J Virol . 2005 May; 79(11):6909-17. PMID: 15890930
Monoclonal antibodies (MAbs) directed against epitopes in the V2 domain of human immunodeficiency virus type 1 gp120 often possess neutralizing activity, but these generally are highly type specific, neutralize only...
9.
Krachmarov C, Pinter A, Honnen W, Gorny M, Nyambi P, Zolla-Pazner S, et al.
J Virol . 2004 Dec; 79(2):780-90. PMID: 15613306
Sera from human immunodeficiency virus type 1 (HIV-1)-infected North American patients recognized a fusion protein expressing a V3 loop from a clade B primary isolate virus (JR-CSF) but not from...
10.
Pinter A, Honnen W, He Y, Gorny M, Zolla-Pazner S, Kayman S
J Virol . 2004 Apr; 78(10):5205-15. PMID: 15113902
A major problem hampering the development of an effective vaccine against human immunodeficiency virus type 1 (HIV-1) is the resistance of many primary viral isolates to antibody-mediated neutralization. To identify...