William Hennah
Overview
Explore the profile of William Hennah including associated specialties, affiliations and a list of published articles.
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28
Citations
925
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Recent Articles
1.
Williams A, Chen J, Coley K, Batini C, Izquierdo A, Packer R, et al.
Nat Commun
. 2023 Oct;
14(1):6713.
PMID: 37872160
Thyroid hormones play a critical role in regulation of multiple physiological functions and thyroid dysfunction is associated with substantial morbidity. Here, we use electronic health records to undertake a genome-wide...
2.
Packer R, Williams A, Hennah W, Eisenberg M, Shrine N, Fawcett K, et al.
Bioinformatics
. 2023 Feb;
39(4).
PMID: 36744935
Summary: DeepPheWAS is an R package for phenome-wide association studies that creates clinically curated composite phenotypes and integrates quantitative phenotypes from primary care data, longitudinal trajectories of quantitative measures, disease...
3.
Sinha V, Ukkola-Vuoti L, Ortega-Alonso A, Torniainen-Holm M, Therman S, Tuulio-Henriksson A, et al.
Mol Psychiatry
. 2019 May;
26(3):816-824.
PMID: 31138891
We have previously reported a replicable association between variants at the PDE4D gene and familial schizophrenia in a Finnish cohort. In order to identify the potential functional mutations underlying these...
4.
Dahoun T, Pardinas A, Veronese M, Bloomfield M, Jauhar S, Bonoldi I, et al.
Hum Mol Genet
. 2018 Jun;
27(20):3498-3506.
PMID: 29945223
Whilst the role of the Disrupted-in-Schizophrenia 1 (DISC1) gene in the aetiology of major mental illnesses is debated, the characterization of its function lends it credibility as a candidate. A...
5.
Bradshaw N, Ukkola-Vuoti L, Pankakoski M, Zheutlin A, Ortega-Alonso A, Torniainen-Holm M, et al.
Open Biol
. 2017 Nov;
7(11).
PMID: 29142105
Genetic studies of familial schizophrenia in Finland have observed significant associations with a group of biologically related genes, , , , and , the 'DISC1 network'. Here, we use gene...
6.
Ortega-Alonso A, Ekelund J, Sarin A, Miettunen J, Veijola J, Jarvelin M, et al.
Schizophr Bull
. 2017 May;
43(6):1304-1314.
PMID: 28525603
The current study examined quantitative measures of psychosis proneness in a nonpsychotic population, in order to elucidate their underlying genetic architecture and to observe if there is any commonality to...
7.
Wegelius A, Pankakoski M, Tomppo L, Lehto U, Lonnqvist J, Suvisaari J, et al.
Psychiatry Res
. 2015 Sep;
230(2):194-9.
PMID: 26350705
Pre- and perinatal environmental factors have been shown to increase schizophrenia risk particularly when combined with genetic liability. The investigation of specific gene environment interactions in the etiology of psychiatric...
8.
Ramos A, Rodriguez-Seoane C, Rosa I, Trossbach S, Ortega-Alonso A, Tomppo L, et al.
Hum Mol Genet
. 2014 Jun;
23(22):5859-65.
PMID: 24934694
In a large Scottish pedigree, disruption of the gene coding for DISC1 clearly segregates with major depression, schizophrenia and related mental conditions. Thus, study of DISC1 may provide a clue...
9.
Rossi M, Kilpinen H, Muona M, Surakka I, Ingle C, Lahtinen J, et al.
Eur J Hum Genet
. 2013 Oct;
22(6):840-3.
PMID: 24169524
Disrupted-in-schizophrenia-1 (DISC1) gene has been established as a risk factor for various neuropsychiatric phenotypes. Both coding and regulatory variants in DISC1 have been identified and associated with these phenotypes in...
10.
Bradshaw N, Hennah W, Soares D
Biomol Concepts
. 2013 Oct;
4(5):447-64.
PMID: 24093049
Nuclear distribution element 1 (NDE1, also known as NudE) and NDE-like 1 (NDEL1, also known as Nudel) are paralogous proteins essential for mitosis and neurodevelopment that have been implicated in...