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William Haskins

Explore the profile of William Haskins including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 110
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Recent Articles
1.
Wang B, Kobeissy F, Golpich M, Cai G, Li X, Abedi R, et al.
Molecules . 2024 Mar; 29(5). PMID: 38474636
Aptamers developed using in vitro Systematic Evolution of Ligands by Exponential Enrichment (SELEX) technology are single-stranded nucleic acids 10-100 nucleotides in length. Their targets, often with specificity and high affinity,...
2.
Wang B, Pan X, Teng I, Li X, Kobeissy F, Wu Z, et al.
Angew Chem Int Ed Engl . 2024 Feb; 63(18):e202402007. PMID: 38407551
Pathological hyperphosphorylation and aggregation of microtubule-associated Tau protein contribute to Alzheimer's Disease (AD) and other related tauopathies. Currently, no cure exists for Alzheimer's Disease. Aptamers offer significant potential as next-generation...
3.
Kobeissy F, Arja R, Munoz J, Shear D, Gilsdorf J, Zhu J, et al.
Expert Rev Mol Diagn . 2024 Jan; 24(1-2):67-77. PMID: 38275158
Introduction: Major organ-based in vitro diagnostic (IVD) tests like ALT/AST for the liver and cardiac troponins for the heart are established, but an approved IVD blood test for the brain...
4.
Garland P, Morton M, Haskins W, Zolnourian A, Durnford A, Gaastra B, et al.
Brain Commun . 2020 Apr; 2(1):fcz053. PMID: 32346673
After subarachnoid haemorrhage, prolonged exposure to toxic extracellular haemoglobin occurs in the brain. Here, we investigate the role of haemoglobin neurotoxicity and its prevention. In humans after subarachnoid haemorrhage, haemoglobin...
5.
Haskins W, Ting M, Wood J, Leong C, Crump-Haill O, Bovill I, et al.
Quant Imaging Med Surg . 2019 Dec; 9(11):1891-1895. PMID: 31867238
No abstract available.
6.
Haskins W, Benitez S, Mercado J, Acosta C
Mol Cell Neurosci . 2017 Jul; 83:13-26. PMID: 28676376
Tandem pore-domain Halothane Inhibited K channel (THIK1) is a two-pore-domain potassium channel (K2P) present in dorsal root ganglia (DRG). We previously demonstrated that THIK1 mRNA levels in the DRG dropped...
7.
Raphael I, Webb J, Stuve O, Haskins W, Forsthuber T
Expert Rev Clin Immunol . 2014 Dec; 11(1):69-91. PMID: 25523168
Multiple sclerosis (MS) is an autoimmune inflammatory disease of the central nervous system, which affects over 2.5 million people worldwide. Although MS has been extensively studied, many challenges still remain...
8.
Zhang J, Haskins W
BMC Genomics . 2010 Dec; 11 Suppl 3:S8. PMID: 21143790
Background: The identification and quantification of proteins using label-free Liquid Chromatography/Mass Spectrometry (LC/MS) play crucial roles in biological and biomedical research. Increasing evidence has shown that biomarkers are often low...
9.
Zhang J, Gonzalez E, Hestilow T, Haskins W, Huang Y
Curr Genomics . 2010 Mar; 10(6):388-401. PMID: 20190954
In this review, we will discuss peak detection in Liquid-Chromatography-Mass Spectrometry (LC/MS) from a signal processing perspective. A brief introduction to LC/MS is followed by a description of the major...
10.
Zamilpa R, Rupaimoole R, Phelix C, Somaraki-Cormier M, Haskins W, Asmis R, et al.
Matrix Biol . 2009 Jun; 28(6):347-53. PMID: 19505574
Transforming growth factor beta-induced protein (TGFBIp), is secreted into the extracellular space. When fragmentation of C-terminal portions is blocked, apoptosis is low, even when the protein is overexpressed. If fragmentation...