William H Walker 2nd
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Explore the profile of William H Walker 2nd including associated specialties, affiliations and a list of published articles.
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30
Citations
645
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Recent Articles
1.
Kisamore C, Kisamore C, Walker 2nd W
Cancer Med
. 2024 Oct;
13(20):e70353.
PMID: 39463009
Background: Circadian rhythms are approximately 24-hour cycles in physiological and behavioral processes. They are entrained to the external solar day via blue wavelength light. Disruptions in these intrinsic rhythms can...
2.
Liu J, Walker 2nd W, Melendez-Fernandez O, Bumgarner J, Zhang N, Walton J, et al.
Exp Neurol
. 2024 Apr;
377:114796.
PMID: 38677449
Circadian rhythms are endogenous biological cycles that regulate physiology and behavior and are set to precisely 24-h by light exposure. Light at night (LAN) dysregulates physiology and function including immune...
3.
Liu J, Bumgarner J, Walker 2nd W, Melendez-Fernandez O, Walton J, DeVries A, et al.
Sci Rep
. 2024 Apr;
14(1):7760.
PMID: 38565934
Disrupted or atypical light-dark cycles disrupts synchronization of endogenous circadian clocks to the external environment; extensive circadian rhythm desynchrony promotes adverse health outcomes. Previous studies suggest that disrupted circadian rhythms...
4.
Walton J, Walker 2nd W, Nelson R, DeVries A
Sci Rep
. 2024 Jan;
14(1):848.
PMID: 38191908
Despite its demonstrated biological significance, time of day is a broadly overlooked biological variable in preclinical and clinical studies. How time of day affects the influence of peripheral tumors on...
5.
Kisamore C, Elliott B, DeVries A, Nelson R, Walker 2nd W
Pharmaceutics
. 2023 Aug;
15(8).
PMID: 37631237
Circadian rhythms are internal manifestations of the 24-h solar day that allow for synchronization of biological and behavioral processes to the external solar day. This precise regulation of physiology and...
6.
Bumgarner J, Walker 2nd W, Quintana D, White R, Richmond A, Melendez-Fernandez O, et al.
iScience
. 2023 Aug;
26(7):106996.
PMID: 37534143
The structure and function of the cardiovascular system are modulated across the day by circadian rhythms, making this system susceptible to circadian rhythm disruption. Recent evidence demonstrated that short-term exposure...
7.
Liu J, Walton J, Bumgarner J, Walker 2nd W, Melendez-Fernandez O, DeVries A, et al.
Chronobiol Int
. 2022 Oct;
39(12):1674-1683.
PMID: 36268694
Circadian rhythms are endogenous biological cycles that regulate physiology and behavior for optimal adaptive function and survival; they are synchronized to precisely 24 hours by daily light exposure. Disruption of...
8.
Nelson R, Bumgarner J, Liu J, Love J, Melendez-Fernandez O, Becker-Krail D, et al.
BMC Biol
. 2022 Jun;
20(1):142.
PMID: 35705939
Background: Circadian rhythms are important for all aspects of biology; virtually every aspect of biological function varies according to time of day. Although this is well known, variation across the...
9.
Becker-Krail D, Walker 2nd W, Nelson R
Front Physiol
. 2022 May;
13:886704.
PMID: 35574492
Circadian rhythms convergently evolved to allow for optimal synchronization of individuals' physiological and behavioral processes with the Earth's 24-h periodic cycling of environmental light and temperature. Whereas the suprachiasmatic nucleus...
10.
Walker 2nd W, Sprowls S, Bumgarner J, Liu J, Melendez-Fernandez O, Walton J, et al.
Front Oncol
. 2021 Dec;
11:752331.
PMID: 34956876
Chemotherapy is more effective in the treatment of peripheral tumors than brain metastases, likely reflecting the reduced ability of chemotherapy to cross the blood-brain barrier (BBB) and blood-tumor barrier at...