William H DePas
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Explore the profile of William H DePas including associated specialties, affiliations and a list of published articles.
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12
Citations
332
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Recent Articles
1.
Ren X, Clark R, Bansah D, Varner E, Tiffany C, Jaswal K, et al.
bioRxiv
. 2024 Nov;
PMID: 39502362
Antimicrobial resistance is an urgent threat to human health. Asymptomatic colonization is often critical for persistence of antimicrobial-resistant pathogens. Gut colonization by the antimicrobial-resistant priority pathogen is associated with increased...
2.
Morris A, Yau Y, DePas W, Waters V
Heliyon
. 2024 Jun;
10(11):e32424.
PMID: 38933957
Current biofilm modelling of the opportunistic pathogen, (PA) in people with cystic fibrosis (PwCF) is limited in its ability to mimic the complexities of the cystic fibrosis (CF) lung environment....
3.
Armbruster C, Marshall C, Garber A, Melvin J, Zemke A, Moore J, et al.
Cell Rep
. 2021 Oct;
37(3):109829.
PMID: 34686349
Pseudomonas aeruginosa notoriously adapts to the airways of people with cystic fibrosis (CF), yet how infection-site biogeography and associated evolutionary processes vary as lifelong infections progress remains unclear. Here we...
4.
OToole G, Crabbe A, Kummerli R, LiPuma J, Bomberger J, Davies J, et al.
mBio
. 2021 Sep;
12(5):e0176321.
PMID: 34544277
A recent workshop titled "Developing Models to Study Polymicrobial Infections," sponsored by the Dartmouth Cystic Fibrosis Center (DartCF), explored the development of new models to study the polymicrobial infections associated...
5.
Wells A, Grimes K, Kim K, Branche E, Bakkenist C, DePas W, et al.
PLoS Pathog
. 2021 Jan;
17(1):e1009252.
PMID: 33513208
Neonatal echovirus infections are characterized by severe hepatitis and neurological complications that can be fatal. Here, we show that expression of the human homologue of the neonatal Fc receptor (hFcRn),...
6.
DePas W, Bergkessel M, Newman D
mBio
. 2019 Aug;
10(4).
PMID: 31409683
Nontuberculous mycobacteria (NTM) are emerging opportunistic pathogens that colonize household water systems and cause chronic lung infections in susceptible patients. The ability of NTM to form surface-attached biofilms in the...
7.
DePas W, Starwalt-Lee R, Van Sambeek L, Kumar S, Gradinaru V, Newman D
mBio
. 2016 Sep;
7(5).
PMID: 27677788
Importance: The advent of metagenomic and metatranscriptomic analyses has improved our understanding of microbial communities by empowering us to identify bacteria, calculate their abundance, and profile gene expression patterns in...
8.
Hufnagel D, DePas W, Chapman M
Microbiol Spectr
. 2015 Jul;
3(3).
PMID: 26185090
Escherichia coli is one of the world's best-characterized organisms, because it has been extensively studied for over a century. However, most of this work has focused on E. coli grown...
9.
DePas W, Syed A, Sifuentes M, Lee J, Warshaw D, Saggar V, et al.
Appl Environ Microbiol
. 2014 Sep;
80(22):7079-87.
PMID: 25192998
Enteric bacteria, such as Escherichia coli, are exposed to a variety of stresses in the nonhost environment. The development of biofilms provides E. coli with resistance to environmental insults, such...
10.
Hufnagel D, DePas W, Chapman M
J Bacteriol
. 2014 Aug;
196(21):3690-9.
PMID: 25112475
The bacterial extracellular matrix encases cells and protects them from host-related and environmental insults. The Escherichia coli master biofilm regulator CsgD is required for the production of the matrix components...