William Gottschalk
Overview
Explore the profile of William Gottschalk including associated specialties, affiliations and a list of published articles.
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7
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243
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Recent Articles
1.
Zeng Y, Chen H, Liu X, Song Z, Yao Y, Lei X, et al.
Heliyon
. 2024 Jan;
10(1):e23691.
PMID: 38192771
It is long observed that females tend to live longer than males in nearly every country. However, the underlying mechanism remains elusive. In this study, we discovered that genetic associations...
2.
Zeng Y, Nie C, Min J, Chen H, Liu X, Ye R, et al.
JAMA Netw Open
. 2018 Oct;
1(4):e181670.
PMID: 30294719
Importance: Sex differences in genetic associations with human longevity remain largely unknown; investigations on this topic are important for individualized health care. Objective: To explore sex differences in genetic associations...
3.
Zhao X, Liu X, Zhang A, Chen H, Huo Q, Li W, et al.
Aging (Albany NY)
. 2018 Jun;
10(6):1206-1222.
PMID: 29883365
Copy number variations (CNVs) have been shown to cause numerous diseases, however, their roles in human lifespan remain elusive. In this study, we investigate the association of CNVs with longevity...
4.
Roses A, Sundseth S, Saunders A, Gottschalk W, Burns D, Lutz M
Alzheimers Dement
. 2016 May;
12(6):687-94.
PMID: 27154058
The methodology of Genome-Wide Association Screening (GWAS) has been applied for more than a decade. Translation to clinical utility has been limited, especially in Alzheimer's Disease (AD). It has become...
5.
Zeng Y, Nie C, Min J, Liu X, Li M, Chen H, et al.
Sci Rep
. 2016 Feb;
6:21243.
PMID: 26912274
Only two genome-wide significant loci associated with longevity have been identified so far, probably because of insufficient sample sizes of centenarians, whose genomes may harbor genetic variants associated with health...
6.
Zeng Y, Chen H, Ni T, Ruan R, Nie C, Liu X, et al.
Rejuvenation Res
. 2015 Sep;
19(3):195-203.
PMID: 26414954
On the basis of the genotypic/phenotypic data from Chinese Longitudinal Healthy Longevity Survey (CLHLS) and Cox proportional hazard model, the present study demonstrates that interactions between carrying FOXO1A-209 genotypes and...
7.
Linnertz C, Anderson L, Gottschalk W, Crenshaw D, Lutz M, Allen J, et al.
Alzheimers Dement
. 2014 Jan;
10(5):541-51.
PMID: 24439168
Background: We investigated the genomic region spanning the Translocase of the Outer Mitochondrial Membrane 40-kD (TOMM40) and Apolipoprotein E (APOE) genes, that has been associated with the risk and age...