William E Haskins
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Explore the profile of William E Haskins including associated specialties, affiliations and a list of published articles.
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30
Citations
355
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Recent Articles
1.
Yang Z, Arja R, Zhu T, Sarkis G, Patterson R, Romo P, et al.
Int J Mol Sci
. 2022 Aug;
23(16).
PMID: 36012232
Glial fibrillary acidic protein (GFAP) is the major intermediate filament III protein of astroglia cells which is upregulated in traumatic brain injury (TBI). Here we reported that GFAP is truncated...
2.
Sarkis G, Lees-Gayed N, Banoub J, Abbatielo S, Robertson C, Haskins W, et al.
Mol Neurobiol
. 2021 Nov;
59(2):731-747.
PMID: 34762230
Traumatic brain injury (TBI) is a major neurological disorder without FDA-approved therapies. In this study, we have examined the concept that TBI might trigger global brain proteolysis in the acute...
3.
Linz T, Yeo D, Hong Q, Zmolek W, McFarland J, Barfield R, et al.
Antibodies (Basel)
. 2019 Sep;
7(4).
PMID: 31544890
We hypothesized that systematic liquid chromatography-tandem mass spectrometry investigations of an antibody-drug conjugate (ADC), its small and large molecular components, and surrogate small-molecule conjugates might comprise a simple and efficient...
4.
Huang B, Kim Y, Banas S, Barfield R, Drake P, Rupniewski I, et al.
MAbs
. 2018 Sep;
10(8):1182-1189.
PMID: 30252630
The advantages of site-specific over stochastic bioconjugation technologies include homogeneity of product, minimal perturbation of protein structure/function, and - increasingly - the ability to perform structure activity relationship studies at...
5.
Tsai T, Hao Z, Hong Q, Moore B, Stella C, Zhang J, et al.
Sci Rep
. 2017 Aug;
7(1):7896.
PMID: 28801661
Peptide mapping with liquid chromatography-tandem mass spectrometry (LC-MS/MS) is an important analytical method for characterization of post-translational and chemical modifications in therapeutic proteins. Despite its importance, there is currently no...
6.
Raphael I, Webb J, Gomez-Rivera F, Chase Huizar C, Gupta R, Arulanandam B, et al.
Front Immunol
. 2017 Aug;
8:812.
PMID: 28769926
There is an urgent need in multiple sclerosis (MS) patients to develop biomarkers and laboratory tests to improve early diagnosis, predict clinical relapses, and optimize treatment responses. In healthy individuals,...
7.
Cantres-Rosario Y, Acevedo-Mariani F, Perez-Laspiur J, Haskins W, Plaud M, Cantres-Rosario Y, et al.
PLoS One
. 2017 Jul;
12(7):e0181779.
PMID: 28746408
Objective: HIV-infected monocytes can infiltrate the blood brain barrier as differentiated macrophages to the central nervous system, becoming the primary source of viral and cellular neurotoxins. The final outcome is...
8.
Morlett-Chavez J, Ascacio-Martinez J, Haskins W, Acuna-Askar K, Barrera-Saldana H
Pol J Microbiol
. 2017 Jul;
66(2):189-199.
PMID: 28735314
Pseudomonas putida strain (HM346961) was isolated from a consortium of bacteria acclimatized to unleaded gasoline-contaminated water. The consortium can efficiently remove benzene, toluene, ethylbenzene and xylene (BTEX) isomers, and a...
9.
Ortiz C, Morales L, Sastre M, Haskins W, Matta J
Evid Based Complement Alternat Med
. 2016 Jun;
2016:3696232.
PMID: 27293457
Sandalwood essential oil (SEO) is extracted from Santalum trees. Although α-santalol, a main constituent of SEO, has been studied as a chemopreventive agent, the genotoxic activity of the whole oil...
10.
Evans T, Van Remmen H, Purkar A, Mahesula S, Gelfond J, Sabia M, et al.
Transl Proteom
. 2015 Jul;
3:10-21.
PMID: 26157646
Short-term increases in oxidative stress and decreases in motor function, including debilitating effects on balance and motor control, can occur following primary mild traumatic brain injuries (mTBI). However, the long-term...