William D Thomas Jr
Overview
Explore the profile of William D Thomas Jr including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
1288
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0
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Recent Articles
1.
Giuntini S, Stoppato M, Sedic M, Ejemel M, Pondish J, Wisheart D, et al.
Infect Immun
. 2018 Nov;
86(12).
PMID: 30459206
No abstract available.
2.
Giuntini S, Stoppato M, Sedic M, Ejemel M, Pondish J, Wisheart D, et al.
Infect Immun
. 2018 Jun;
86(8).
PMID: 29866909
Enterotoxigenic (ETEC) causes diarrheal illness in infants in the developing world and travelers to countries where the disease is endemic, including military personnel. ETEC infection of the host involves colonization...
3.
Pierce B, Boucher E, Piepenbrink K, Ejemel M, Rapp C, Thomas Jr W, et al.
J Virol
. 2017 Aug;
91(20).
PMID: 28794021
Despite recent advances in therapeutic options, hepatitis C virus (HCV) remains a severe global disease burden, and a vaccine can substantially reduce its incidence. Due to its extremely high sequence...
4.
Shandilya S, Yilmaz N, Sadowski A, Monir E, Schiller Z, Thomas Jr W, et al.
J Mol Recognit
. 2016 Nov;
30(5).
PMID: 27859766
The murine monoclonal antibody LA-2 recognizes a clinically protective epitope on outer surface protein (OspA) of Borrelia burgdorferi, the causative agent of Lyme disease in North America. Human antibody equivalence...
5.
Wang Y, Kern A, Boatright N, Schiller Z, Sadowski A, Ejemel M, et al.
J Infect Dis
. 2016 Jun;
214(2):205-11.
PMID: 27338767
Background: Tick transmission of Borrelia spirochetes to humans results in significant morbidity from Lyme disease worldwide. Serum concentrations of antibodies against outer surface protein A (OspA) were shown to correlate...
6.
Casaz P, Boucher E, Wollacott R, Pierce B, Rivera R, Sedic M, et al.
MAbs
. 2014 Dec;
6(6):1533-9.
PMID: 25484044
A common challenge encountered during development of high concentration monoclonal antibody formulations is preventing self-association. Depending on the antibody and its formulation, self-association can be seen as aggregation, precipitation, opalescence...
7.
Wollacott R, Casaz P, Morin T, Zhu H, Anderson R, Babcock G, et al.
MAbs
. 2013 Sep;
5(6):925-35.
PMID: 23995619
Size exclusion high performance liquid chromatography analysis of a human monoclonal antibody (mAb) showed the presence of a new species that eluted with a retention time between the dimeric and...
8.
Lowy I, Molrine D, Leav B, Blair B, Baxter R, Gerding D, et al.
N Engl J Med
. 2010 Jan;
362(3):197-205.
PMID: 20089970
Background: New therapies are needed to manage the increasing incidence, severity, and high rate of recurrence of Clostridium difficile infection. Methods: We performed a randomized, double-blind, placebo-controlled study of two...
9.
Broering T, Garrity K, Boatright N, Sloan S, Sandor F, Thomas Jr W, et al.
J Virol
. 2009 Sep;
83(23):12473-82.
PMID: 19759151
Nearly all livers transplanted into hepatitis C virus (HCV)-positive patients become infected with HCV, and 10 to 25% of reinfected livers develop cirrhosis within 5 years. Neutralizing monoclonal antibody could...
10.
Sloan S, Hanlon C, Weldon W, Niezgoda M, Blanton J, Self J, et al.
Vaccine
. 2007 Jan;
25(15):2800-10.
PMID: 17240489
Rabies is a zoonosis that results in millions of human exposures worldwide each year. Human monoclonal antibodies (HuMAbs) that neutralize rabies virus may represent one viable strategy for post-exposure prophylaxis...