William A McLaughlin
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Explore the profile of William A McLaughlin including associated specialties, affiliations and a list of published articles.
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19
Citations
260
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Recent Articles
1.
Huang G, Parry T, McLaughlin W
Bioengineering (Basel)
. 2023 Dec;
10(12).
PMID: 38135968
Background: Model quality assessments via computational methods which entail comparisons of the modeled structures to the experimentally determined structures are essential in the field of protein structure prediction. The assessments...
2.
Gnilopyat S, DePietro P, Parry T, McLaughlin W
Biomolecules
. 2022 Nov;
12(11).
PMID: 36358909
We present the Pharmacorank search tool as an objective means to obtain prioritized protein drug targets and their associated medications according to user-selected diseases. This tool could be used to...
3.
Toth J, DePietro P, Haas J, McLaughlin W
Bioinformatics
. 2020 Aug;
37(3):351-359.
PMID: 32780798
Motivation: Methods to assess the quality of protein structure models are needed for user applications. To aid with the selection of structure models and further inform the development of structure...
4.
Piper B, Alinea A, Wroblewski J, Graham S, Chung D, McCutcheon L, et al.
Pharmacy (Basel)
. 2019 Dec;
8(1).
PMID: 31861770
Goodman and Gilman's (PBT) has been a cornerstone in the education of pharmacists, physicians, and pharmacologists for decades. The objectives of this study were to describe and evaluate the 13...
5.
Khan S, McLaughlin W, Kumar R
Sci Rep
. 2017 Nov;
7(1):15440.
PMID: 29133811
Intrinsically disordered (ID) regions of the transcription factor proteins have much larger frequency of phosphorylation sites than ordered regions, suggesting an important role in their regulatory capacity. Consistent with this...
6.
Farrell M, Wallace S, Clarke S, Tarafder M, McLaughlin W
J Prim Care Community Health
. 2013 Dec;
5(2):134-8.
PMID: 24327597
Previous studies have described an increased risk of developing an additional connective tissue disease (CTD) when one such ailment is present. We examine here the likelihood that individuals with systemic...
7.
DePietro P, Julfayev E, McLaughlin W
BMC Struct Biol
. 2013 Oct;
13:24.
PMID: 24139526
Background: Protein Structure Initiative:Biology (PSI:Biology) is the third phase of PSI where protein structures are determined in high-throughput to characterize their biological functions. The transition to the third phase entailed...
8.
Julfayev E, McLaughlin R, Tao Y, McLaughlin W
J Struct Funct Genomics
. 2012 Jan;
13(2):101-10.
PMID: 22270457
The KB-Rank tool was developed to help determine the functions of proteins. A user provides text query and protein structures are retrieved together with their functional annotation categories. Structures and...
9.
Gabanyi M, Adams P, Arnold K, Bordoli L, Carter L, Flippen-Andersen J, et al.
J Struct Funct Genomics
. 2011 Apr;
12(2):45-54.
PMID: 21472436
The Protein Structure Initiative's Structural Biology Knowledgebase (SBKB, URL: http://sbkb.org ) is an open web resource designed to turn the products of the structural genomics and structural biology efforts into...
10.
Julfayev E, McLaughlin R, Tao Y, McLaughlin W
J Struct Funct Genomics
. 2011 Mar;
12(1):9-20.
PMID: 21445639
The three dimensional atomic structures of proteins provide information regarding their function; and codified relationships between structure and function enable the assessment of function from structure. In the current study,...