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Willem J van den Brink

Explore the profile of Willem J van den Brink including associated specialties, affiliations and a list of published articles. Areas
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Citations 55
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Recent Articles
1.
Dessing M, van den Broek T, Hoevenaars F, van den Brink W, Rundle M, Frost G, et al.
Eur J Nutr . 2025 Mar; 64(3):106. PMID: 40035864
Purpose: Assessing the health impacts of nutritional interventions in metabolically compromised but otherwise healthy individuals is challenging, necessitating sensitive tools. Phenotypic flexibility offers an innovative way to measure homeostatic capacity...
2.
van den Brink W, Oosterman J, Smid D, de Vries H, Atsma D, Overeem S, et al.
Digit Health . 2025 Feb; 11:20552076241288724. PMID: 39980570
Digital biomarkers are quantifiable and objective indicators of a person's physiological function, behavioral state or treatment response, that can be captured using connected sensor technologies such as wearable devices and...
3.
van den Brink W, van den Broek T, Wopereis S, Difrancesco S, van der Horst F, de Hoogh I
Maturitas . 2025 Jan; 194:108188. PMID: 39778441
Objectives: Type 2 diabetes is a highly prevalent age-related chronic condition, with complex and heterogeneous pathogenesis. A 5-point oral glucose tolerance test can identify type 2 diabetes subtypes or "diabetypes"...
4.
Cuperus L, Bult L, van Zelst C, van den Brink W, Kamstra K, van den Broek T, et al.
ERJ Open Res . 2024 Nov; 10(6). PMID: 39588079
https://bit.ly/4cPnHUK.
5.
Wei J, van den Broek T, van Baardewijk J, van Stokkum R, Kamstra R, Rikken L, et al.
Sci Rep . 2024 Oct; 14(1):23098. PMID: 39367187
Successful implementation of remote monitoring of vital signs outside of the hospital setting hinges on addressing three crucial unmet needs: longer-term wear, skin comfort and signal quality. Earlier, we developed...
6.
van den Brink W, van den Broek T, Palmisano S, Wopereis S, de Hoogh I
Nutrients . 2022 Nov; 14(21). PMID: 36364728
Digital health technologies may support the management and prevention of disease through personalized lifestyle interventions. Wearables and smartphones are increasingly used to continuously monitor health and disease in everyday life,...
7.
van der Haar S, Hoevenaars F, van den Brink W, van den Broek T, Timmer M, Boorsma A, et al.
JMIR Form Res . 2021 Jun; 5(6):e25043. PMID: 34185002
Background: Dietary quality plays an essential role in the prevention and management of metabolic syndrome (MetS). Objective: The aim of this pilot study is to organize personalized dietary advice in...
8.
Pasman W, Memelink R, Bosch J, Begieneman M, van den Brink W, Weijs P, et al.
Nutrients . 2020 Oct; 12(10). PMID: 33003389
(1) Background: Recent research showed that subtypes of patients with type 2 diabetes may differ in response to lifestyle interventions based on their organ-specific insulin resistance (IR). (2) Methods: 123...
9.
Hoevenaars F, Esser D, Schutte S, Priebe M, Vonk R, van den Brink W, et al.
J Nutr . 2019 Sep; 149(12):2133-2144. PMID: 31504709
Background: Whole grain wheat (WGW) consumption is associated with health benefits in observational studies. However, WGW randomized controlled trial (RCT) studies show mixed effects. Objectives: The health impact of WGW...
10.
van den Brink W, Hartman R, van den Berg D, Flik G, Gonzalez-Amoros B, Koopman N, et al.
CPT Pharmacometrics Syst Pharmacol . 2019 Jan; 8(2):107-117. PMID: 30680960
A key challenge in the development of central nervous system drugs is the availability of drug target specific blood-based biomarkers. As a new approach, we applied cluster-based pharmacokinetic/pharmacodynamic (PK/PD) analysis...