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Wiebke Wlotzka

Explore the profile of Wiebke Wlotzka including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Herzog V, Reichholf B, Neumann T, Rescheneder P, Bhat P, Burkard T, et al.
Nat Methods . 2017 Sep; 14(12):1198-1204. PMID: 28945705
Gene expression profiling by high-throughput sequencing reveals qualitative and quantitative changes in RNA species at steady state but obscures the intracellular dynamics of RNA transcription, processing and decay. We developed...
2.
Leung E, Schneider C, Yan F, Mohi-El-Din H, Kudla G, Tuck A, et al.
Nucleic Acids Res . 2014 Aug; 42(16):10698-710. PMID: 25159613
The RNA component of signal recognition particle (SRP) is transcribed by RNA polymerase III, and most steps in SRP biogenesis occur in the nucleolus. Here, we examine processing and quality...
3.
Hazelbaker D, Marquardt S, Wlotzka W, Buratowski S
Mol Cell . 2012 Nov; 49(1):55-66. PMID: 23177741
The essential helicase-like protein Sen1 mediates termination of RNA Polymerase II (Pol II) transcription at snoRNAs and other noncoding RNAs in yeast. A mutation in the Pol II subunit Rpb1...
4.
Swiatkowska A, Wlotzka W, Tuck A, Barrass J, Beggs J, Tollervey D
RNA . 2012 Oct; 18(12):2187-200. PMID: 23093724
Pre-ribosomal particles undergo numerous structural changes during maturation, but their high complexity and short lifetimes make these changes very difficult to follow in vivo. In consequence, pre-ribosome structure and composition...
5.
Schneider C, Kudla G, Wlotzka W, Tuck A, Tollervey D
Mol Cell . 2012 Sep; 48(3):422-33. PMID: 23000172
The exosome plays major roles in RNA processing and surveillance but the in vivo target range and substrate acquisition mechanisms remain unclear. Here we apply in vivo RNA crosslinking (CRAC)...
6.
Wlotzka W, Kudla G, Granneman S, Tollervey D
EMBO J . 2011 Apr; 30(9):1790-803. PMID: 21460797
A key question in nuclear RNA surveillance is how target RNAs are recognized. To address this, we identified in vivo binding sites for nuclear RNA surveillance factors, Nrd1, Nab3 and...