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Werner Steimer

Explore the profile of Werner Steimer including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 392
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Recent Articles
1.
Hart X, Amann F, Baumann P, Havemann-Reinecke U, Schoretsanitis G, Steimer W, et al.
Ther Drug Monit . 2025 Feb; 47(2):199-210. PMID: 39950917
Background: Therapeutic drug monitoring (TDM) is essential for controlling pharmacogenetic and pharmacokinetic variations and for optimizing pharmacotherapy. However, its value is often underestimated because of nonsystematic recommendations for target ranges...
2.
Hart X, Grunder G, Ansermot N, Conca A, Corruble E, Crettol S, et al.
World J Biol Psychiatry . 2024 Jun; 25(9):451-536. PMID: 38913780
Background: For psychotic disorders (i.e. schizophrenia), pharmacotherapy plays a key role in controlling acute and long-term symptoms. To find the optimal individual dose and dosage strategy, specialised tools are used....
3.
Scherf-Clavel M, Baumann P, Hart X, Schneider H, Schoretsanitis G, Steimer W, et al.
Ther Drug Monit . 2023 Mar; 46(2):143-154. PMID: 36941240
Purpose: Therapeutic drug monitoring (TDM) is a well-established tool for guiding psychopharmacotherapy and improving patient care. Despite their established roles in the prescription of psychotropic drugs, the "behind the curtain"...
4.
Schreyer K, Leucht S, Heres S, Steimer W
Psychopharmacology (Berl) . 2023 Feb; 240(4):899-908. PMID: 36757449
Rationale: Weight gain is a frequent side effect of treatment with SGAs (second-generation antipsychotics) and a leading cause for nonadherence. Several candidate genes have been identified that could influence the...
5.
Schneider H, Hess C, Kessler A, Steimer W
Ther Drug Monit . 2021 Dec; 44(1):230-240. PMID: 34923543
Background: For many antibiotics, the convenient one-fits-all dosing regimen had to be abandoned. Owing to highly variable pharmacokinetics, therapeutic drug monitoring has become an indispensable prerequisite. It is based on...
6.
Matthaei J, Brockmoller J, Steimer W, Pischa K, Leucht S, Kullmann M, et al.
Front Pharmacol . 2021 Jun; 12:688950. PMID: 34093211
The tricyclic antidepressant amitriptyline is frequently prescribed but its use is limited by its narrow therapeutic range and large variation in pharmacokinetics. Apart from interindividual differences in the activity of...
7.
Ahmad-Nejad P, Ashavaid T, Salinas A, Huggett J, Harris K, Linder M, et al.
Clin Chim Acta . 2021 May; 519:239-246. PMID: 33971158
The development and performance of molecular genetic assays has required increasingly complex quality assurance in recent years and continues to pose new challenges. Quality management officers, as well as academic...
8.
Schoretsanitis G, Baumann P, Conca A, Dietmaier O, Giupponi G, Grunder G, et al.
Ther Drug Monit . 2020 Nov; 43(1):79-102. PMID: 33196621
Background: The use of therapeutic drug monitoring (TDM) to guide treatment with long-acting injectable (LAI) antipsychotics, which are increasingly prescribed, remains a matter of debate. The aim of this review...
9.
Ortner M, Stange M, Schneider H, Schroder C, Buerger K, Muller C, et al.
Drug Des Devel Ther . 2020 Aug; 14:3251-3262. PMID: 32848364
Background: The efficacy of acetylcholinesterase inhibitors (AChE-I) might depend on blood concentration. While rivastigmine metabolism is independent of the cytochrome P450 system, its isoenzymes, especially CYP2D6, metabolize donepezil. polymorphisms can...
10.
Ortner M, Stange M, Schneider H, Schroeder C, Buerger K, Muller C, et al.
Front Pharmacol . 2020 Jun; 11:691. PMID: 32508640
Background: Acetylcholinesterase inhibitors (AChE-I) are recommended for the treatment of cognitive symptoms but also of behavioral and psychological symptoms in dementia. They are widely used not only in Alzheimer's disease,...