Wenliang Hao
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Explore the profile of Wenliang Hao including associated specialties, affiliations and a list of published articles.
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8
Citations
62
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Recent Articles
1.
Hao W, Yang S, Sheng Y, Ye C, Han L, Zhou Z, et al.
Biotechnol Prog
. 2025 Feb;
:e70007.
PMID: 39968680
Bacillus subtilis is a favored chassis for high productivity of several high value-added product in synthetic biology. Efficient production of recombinant proteins is critical but challenging using this chassis because...
2.
Hao W, Cui W, Liu Z, Suo F, Wu Y, Han L, et al.
Adv Sci (Weinh)
. 2024 Apr;
11(22):e2309767.
PMID: 38602436
Base editors (BEs) are widely used as revolutionary genome manipulation tools for cell evolution. To screen the targeted individuals, it is often necessary to expand the editing window to ensure...
3.
Hao W, Cui W, Suo F, Han L, Cheng Z, Zhou Z
Chem Sci
. 2022 Dec;
13(48):14395-14409.
PMID: 36545152
The functionally evolved bacterial chassis is of great importance to manufacture a group of assorted high value-added chemicals, from small molecules to biologically active macromolecules. However, the current evolution frameworks...
4.
Zhou Y, Lv H, Li H, Li J, Yan Y, Liu F, et al.
Appl Environ Microbiol
. 2021 Oct;
87(24):e0175821.
PMID: 34613761
Nitroreductases (NTRs) catalyze the reduction of a wide range of nitro-compounds and quinones using NAD(P)H. Although the physiological functions of these enzymes remain obscure, a tentative function of resistance to...
5.
Hao W, Cui W, Cheng Z, Han L, Suo F, Liu Z, et al.
Nucleic Acids Res
. 2021 Aug;
49(16):9594-9605.
PMID: 34390349
Protein evolution has significantly enhanced the development of life science. However, it is difficult to achieve in vitro evolution of some special proteins because of difficulties with heterologous expression, purification,...
6.
Hao W, Suo F, Lin Q, Chen Q, Zhou L, Liu Z, et al.
Front Bioeng Biotechnol
. 2020 Sep;
8:524676.
PMID: 32984297
is an important Gram-positive bacterium for industrial biotechnology, which has been widely used to produce diverse high-value added chemicals and industrially and pharmaceutically relevant proteins. Robust and versatile toolkits for...
7.
Han L, Cui W, Lin Q, Chen Q, Suo F, Ma K, et al.
Front Bioeng Biotechnol
. 2020 Apr;
8:193.
PMID: 32266230
A robust and portable expression system is of great importance in enzyme production, metabolic engineering, and synthetic biology, which maximizes the performance of the engineered system. In this study, a...
8.
Han L, Cui W, Suo F, Miao S, Hao W, Chen Q, et al.
Microb Cell Fact
. 2019 May;
18(1):96.
PMID: 31142347
Background: Promoter evolution by synthetic promoter library (SPL) is a powerful approach to development of functional synthetic promoters to synthetic biology. However, it requires much tedious and time-consuming screenings because...
9.
Cui W, Suo F, Cheng J, Han L, Hao W, Guo J, et al.
Microb Biotechnol
. 2018 Jul;
11(5):930-942.
PMID: 29984489
Nattokinase (NK) is an important serine-protease with direct fibrinolytic activity involving the prevention of cardiovascular disease as an antithrombotic agent. Dozens of studies have focused on the characterization of intrinsic...