Wenlang Liu
Overview
Explore the profile of Wenlang Liu including associated specialties, affiliations and a list of published articles.
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4
Citations
9
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Recent Articles
1.
Liu Z, Liu W, Shen X, Jiang T, Li X, Liu H, et al.
Sci Rep
. 2025 Feb;
15(1):6926.
PMID: 40011494
The emergence of targeted therapies for MET exon 14 (METex14) skipping mutations has significantly changed the treatment landscape for NSCLC and other solid tumors. The skipping of METex14 results in...
2.
Yuan J, Liu W, Jiang X, Huang Y, Zong L, Ding H, et al.
Sci Rep
. 2024 Jul;
14(1):16680.
PMID: 39030216
The dual activation of glucagon-like peptide-1 receptor (GLP-1R) and glucose-dependent insulinotropic polypeptide receptor (GIPR) has emerged as a promising therapeutic strategy for managing type 2 diabetes and obesity. Tirzepatide, a...
3.
Liu Z, Liang K, Liu W, Jiang T, Zhou R, Duan M, et al.
J Chem Inf Model
. 2023 Jun;
63(13):4147-4157.
PMID: 37357790
The tyrosine-protein kinase Met (c-Met) is an important signaling molecule involved in cellular growth and division. The dysregulation of c-Met may induce many fatal diseases, including non-small cell lung cancer,...
4.
Liu W, Liu Z, Liu H, Westerhoff L, Zheng Z
J Chem Inf Model
. 2022 Oct;
62(22):5645-5665.
PMID: 36282990
Fast and accurate biomolecular free energy estimation has been a significant interest for decades, and with recent advances in computer hardware, interest in new method development in this field has...
5.
Jiang T, Liu Z, Liu W, Chen J, Zheng Z, Duan M
J Chem Inf Model
. 2022 Jul;
62(15):3651-3663.
PMID: 35848778
Protein kinases intrinsically translate their conformations between active and inactive states, which is key to their enzymatic activities. The conformational flipping of the three-residue conservative motif, Asp-Phe-Gly (DFG), is crucial...