Wenjun Le
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Explore the profile of Wenjun Le including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
416
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Recent Articles
11.
Xu J, Zeng S, Li J, Gao L, Le W, Huang X, et al.
Front Cell Dev Biol
. 2022 Feb;
9:813420.
PMID: 35174172
Tumor cells were reported to have perpetual negative surface charges due to elevated glycolysis, and multifunctional nanoprobes (FeO@SiO mNPs) could attach onto tumor cells opposite surface charges. We thus evaluated...
12.
Liu Y, Zhang Y, Mei T, Cao H, Hu Y, Jia W, et al.
Adv Sci (Weinh)
. 2022 Jan;
9(9):e2104299.
PMID: 35092352
Transplanting functional cells to treat myocardial infarction (MI), a major disease threatening human health, has become the focus of global therapy. However, the efficacy has not been well anticipated, partly...
13.
Xu M, Cui R, Ye L, Wang Y, Wang X, Zhang Q, et al.
Mol Ther Nucleic Acids
. 2021 Sep;
26:280-294.
PMID: 34513310
Pancreatic ductal adenocarcinoma (PDAC) is one of most lethal cancers and is projected to be the second leading cause of cancer deaths in the United States by 2030. The lack...
14.
Huang X, Chen Q, Li X, Lin C, Wang K, Luo C, et al.
Nanoscale Res Lett
. 2021 Jul;
16(1):124.
PMID: 34331597
At present, various fluorescent nanomaterials have been designed and synthesized as optical contrast agents for surgical navigation. However, there have been no reports on the preparation of fluorescent contrast agents...
15.
Pang B, Li H, Liu Q, Wu P, Xia T, Zhang X, et al.
Front Med (Lausanne)
. 2021 Jul;
8:689568.
PMID: 34222293
Early identification of coronavirus disease 2019 (COVID-19) patients with worse outcomes may benefit clinical management of patients. We aimed to quantify pneumonia findings on CT at admission to predict progression...
16.
Liu Q, Pang B, Li H, Zhang B, Liu Y, Lai L, et al.
J Thorac Dis
. 2021 Mar;
13(2):1215-1229.
PMID: 33717594
Background: To develop machine learning classifiers at admission for predicting which patients with coronavirus disease 2019 (COVID-19) who will progress to critical illness. Methods: A total of 158 patients with...
17.
Wang J, Mei T, Liu Y, Zhang Y, Zhang Z, Hu Y, et al.
Biomater Sci
. 2021 Mar;
9(11):3968-3978.
PMID: 33666216
Nanoparticle-mediated photothermal therapy (PTT) has shown promising capability for tumor therapy through the high local temperature at the tumor site generated by a photothermal agent (PTA) under visible or near-infrared...
18.
Chen X, Wang T, Le W, Huang X, Gao M, Chen Q, et al.
Theranostics
. 2020 Mar;
10(8):3430-3450.
PMID: 32206100
Reactive oxygen species (ROS) play a crucial role in cancer formation and development, especially cancer metastasis. However, lack of a precise tool, which could accurately distinguish specific types of ROS,...
19.
Wu M, Mei T, Lin C, Wang Y, Chen J, Le W, et al.
ACS Appl Mater Interfaces
. 2020 Mar;
12(14):16031-16039.
PMID: 32186357
Modulating the surface properties of nanoparticles (NPs) is an important approach to accomplish immune escape, prolonged the blood retention time, and enhance the ability of targeted drug delivery. The camouflage...
20.
Wu M, Le W, Mei T, Wang Y, Chen B, Liu Z, et al.
Int J Nanomedicine
. 2019 Jul;
14:4431-4448.
PMID: 31354269
Targeted drug delivery by nanoparticles (NPs) is an essential technique to achieve the ideal therapeutic effect for cancer. However, it requires large amounts of work to imitate the biomarkers on...