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Wenhui Tao

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Citations 222
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Recent Articles
1.
Ding T, Shen W, Tao W, Peng J, Pan M, Qi X, et al.
J Nutr Biochem . 2024 Nov; 136:109807. PMID: 39549858
Fatty liver disease (FLD), a chronic liver disease characterized by excessive lipid deposition, is affecting more and more people worldwide owing to the increasing global incidence of obesity and heavy...
2.
Tao W, Bao J, Xie Y, Ding W, Wu Y, Zhang Y, et al.
Int J Surg . 2024 Jul; 111(1):644-649. PMID: 39023809
Background: Venous thromboembolism is one of the most common and serious complications of cesarean section in parturients. Norepinephrine (NE) has been shown to activate coagulation. The aim of this study...
3.
Xiong D, Han T, Li Y, Hong Y, Li S, Li X, et al.
BMC Cancer . 2024 Jul; 24(1):840. PMID: 39009999
Background: Detection of cancer and identification of tumor origin at an early stage improve the survival and prognosis of patients. Herein, we proposed a plasma cfDNA-based approach called TOTEM to...
4.
Tao W, Xie Y, Bao J, Ding W, Zhang Y, Hu X
BMJ Open . 2024 Jul; 14(7):e083202. PMID: 38991676
Introduction: Peripheral vasodilation causes a redistribution of body temperature from the core to the periphery, resulting in shivering and hypothermia. These are normal pathological and physiological processes during spinal anaesthesia....
5.
Tao W, Xie Y, Ding W, Bao J, Zhang Y, Hu X
Trials . 2024 Jul; 25(1):432. PMID: 38956697
Background: Norepinephrine and phenylephrine are commonly used vasoactive drugs to treat hypotension during the perioperative period. The increased release of endogenous norepinephrine elicits prothrombotic changes, while parturients are generally in...
6.
Huang J, Zhang J, Xu W, Wu Q, Zeng R, Liu Z, et al.
J Med Chem . 2022 Dec; 66(2):1186-1209. PMID: 36516047
Inducing protein degradation by proteolysis targeting chimeras has gained tremendous momentum as a promising novel therapeutic strategy. Here, we report the design, synthesis, and biological characterization of highly potent proteolysis...
7.
Shan X, Zhang J, Wei X, Tao W, Peng K, Liu H, et al.
FASEB J . 2022 Oct; 36(11):e22608. PMID: 36250975
Renal microvascular endothelial cells (RMECs), which are closely related to regulation of vascular reactivity and modulation of inflammation, play a crucial role in the process of renal ischemia and reperfusion...
8.
Hou T, Tian Y, Cao Z, Zhang J, Feng T, Tao W, et al.
Mol Cell . 2022 Oct; 82(21):4099-4115.e9. PMID: 36208627
Nonalcoholic fatty liver disease (NAFLD) is characterized by excessive hepatic lipid accumulation, which can progress to nonalcoholic steatohepatitis (NASH). Histone deacetylase Sirtuin 6 (SIRT6) regulates NAFLD by regulating metabolism-related gene...
9.
Tao W, Li L, Hu J, Xu S, Wang B, Ding J, et al.
Am J Transl Res . 2022 Jun; 14(5):3360-3371. PMID: 35702111
Purpose: Apoptosis induced by excessive endoplasmic reticulum (ER) stress is accompanied by the occurrence and progression of myocardial ischemia/reperfusion (I/R) injury. COX-2 is also known to affect the development of...
10.
Tao W, Zhao D, Li G, Li L, Li S, Ye H, et al.
Acta Pharm Sin B . 2022 May; 12(3):1487-1499. PMID: 35530142
The unique characteristics of the tumor microenvironment (TME) could be exploited to develop antitumor nanomedicine strategies. However, in many cases, the actual therapeutic effect is far from reaching our expectations...