Weng-Onn Lui
Overview
Explore the profile of Weng-Onn Lui including associated specialties, affiliations and a list of published articles.
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61
Citations
1666
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Recent Articles
11.
Frobom R, Berglund E, Aspinwall C, Lui W, Nilsson I, Larsson C, et al.
Biochem Biophys Res Commun
. 2021 Apr;
557:14-19.
PMID: 33857840
The ATP-regulated K channel (K) plays an essential role in the control of many physiological processes, and contains a ATP-binding site. Tyrosine kinase inhibitors (TKI) are commonly used drugs, that...
12.
Bjorn Andtback H, Bjornhagen-Safwenberg V, Shi H, Lui W, Masucci G, Villabona L
Cancers (Basel)
. 2021 Jan;
13(2).
PMID: 33445741
Merkel cell carcinoma (MCC) is a rare and aggressive skin cancer where Merkel cell Polyomavirus (MCPyV) contributes to the pathogenesis. In an adjuvant setting, radiotherapy (RT) is believed to give...
13.
Huang W, Gao J, Chen Z, Shi H, Yuan J, Cui H, et al.
Cells
. 2020 May;
9(6).
PMID: 32466502
Metabolic reprogramming is a hallmark of cancer cells in response to targeted therapy. Decreased glycolytic activity with enhanced mitochondrial respiration secondary to imatinib has been shown in imatinib-sensitive gastrointestional stromal...
14.
Paulsson J, Wang N, Gao J, Stenman A, Zedenius J, Mu N, et al.
Endocr Relat Cancer
. 2020 Mar;
27(5):295-308.
PMID: 32163919
Mutations in the miRNA enzyme gene DICER1 have been reported in several endocrine malignancies and is associated with the rare tumour-predisposing DICER1 syndrome. DICER1 mutations have been reported in subsets...
15.
Kumar S, Xie H, Shi H, Gao J, Juhlin C, Bjornhagen V, et al.
Int J Cancer
. 2019 Jun;
146(6):1652-1666.
PMID: 31180579
Viruses can inhibit host autophagy through multiple mechanisms, and evasion of autophagy plays an important role in immune suppression and viral oncogenesis. Merkel cell polyomavirus (MCPyV) T-antigens are expressed and...
16.
Regulation of LDHB Plays Distinct Roles in Polyomavirus-Positive and -Negative Merkel Cell Carcinoma
Kumar S, Xie H, Scicluna P, Lee L, Bjornhagen V, Hoog A, et al.
Cancers (Basel)
. 2018 Nov;
10(11).
PMID: 30441870
() is deregulated in multiple tumor types and regulates important targets involved in tumorigenesis and metastasis. This miRNA is highly expressed in Merkel cell carcinoma (MCC) compared to normal skin...
17.
Huang W, Akcakaya P, Gangaev A, Lee L, Zeljic K, Hajeri P, et al.
Exp Cell Res
. 2018 Aug;
371(1):287-296.
PMID: 30149002
The use of imatinib mesylate has greatly improved the clinical outcome for gastrointestinal stromal tumor (GIST) patients. However, imatinib resistance is still a major clinical challenge, and the molecular mechanisms...
18.
Chang R, Li X, Mu N, Hrydziuszko O, Garcia-Majano B, Larsson C, et al.
Int J Oncol
. 2017 Nov;
52(1):55-66.
PMID: 29138809
Ovarian germ cell tumors (OGCTs) and sex cord stromal tumors (SCSTs) are rare gynecologic tumors that are derived from germ and stromal cells, respectively. Unlike their epithelial counterparts, molecular pathogenesis...
19.
Mohammad A, Costa H, Landazuri N, Lui W, Hultenby K, Rahbar A, et al.
J Gen Virol
. 2017 Jun;
98(5):1058-1072.
PMID: 28589873
Human cytomegalovirus (HCMV) infection results in the production of virions, dense bodies (DBs) and non-infectious enveloped particles, all of which incorporate proteins and RNAs that can be transferred to host...
20.
Xie H, Norman I, Hjerpe A, Vladic T, Larsson C, Lui W, et al.
Oncol Lett
. 2017 May;
13(5):3586-3598.
PMID: 28529583
High-risk human papillomavirus (HPV) testing is a recommended triage approach for females with atypical squamous cells of undetermined significance (ASCUS), but due to its poor specificity this approach is not...