Wendy Putnam
Overview
Explore the profile of Wendy Putnam including associated specialties, affiliations and a list of published articles.
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5
Citations
130
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Recent Articles
1.
Sperinde G, Dolton M, Zhang W, Mathews J, Putnam W, Fischer S
Bioanalysis
. 2023 Oct;
15(21):1305-1314.
PMID: 37791725
This paper describes a case study of an antibody therapeutic targeting a membrane-bound receptor, also present in systemic circulation, as a soluble receptor. During phase I studies of astegolimab, nonlinear...
2.
Lee S, Gosselin N, Jomphe C, McKeever K, Putnam W
Clin Pharmacol Drug Dev
. 2022 Jul;
11(11):1264-1272.
PMID: 35908210
Triheptanoin is an odd-carbon, medium-chain triglyceride consisting of three fatty acids with seven carbons each on a glycerol backbone, indicated for the treatment of adult and pediatric patients with long-chain...
3.
Svensson R, Ribbing J, Kotani N, Dolton M, Vadhavkar S, Cheung D, et al.
CPT Pharmacometrics Syst Pharmacol
. 2021 Aug;
10(10):1221-1235.
PMID: 34346168
Identification of covariates, including biomarkers, spirometry, and diaries/questionnaires, that predict asthma exacerbations would allow better clinical predictions, shorter phase II trials and inform decisions on phase III design, and/or initiation...
4.
Simpson E, Flohr C, Eichenfield L, Bieber T, Sofen H, Taieb A, et al.
J Am Acad Dermatol
. 2018 Jan;
78(5):863-871.e11.
PMID: 29353026
Background: Interleukin (IL)-13 plays a key role in type 2 inflammation and is an emerging pathogenic mediator in atopic dermatitis (AD). Objective: We investigated the efficacy and safety of lebrikizumab,...
5.
Ng C, Xiao Y, Putnam W, Lum B, Tropsha A
J Pharm Sci
. 2004 Sep;
93(10):2535-44.
PMID: 15349962
We have developed quantitative structure-pharmacokinetic parameters relationship (QSPKR) models using k-nearest-neighbor (k-NN) and partial least-square (PLS) methods to predict the volume of distribution at steady state (Vss) and clearance (CL)...