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Wen Jen Lin

Explore the profile of Wen Jen Lin including associated specialties, affiliations and a list of published articles. Areas
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Articles 17
Citations 147
Followers 0
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Recent Articles
1.
Lai M, Lin W
Int J Biol Macromol . 2024 Oct; 281(Pt 4):136651. PMID: 39423978
Ovarian cancer is a leading gynecological cancer globally. This study aimed to develop hyaluronic acid-modified polyethylene glycol conjugated zein nanoparticles (zein-PEG/HA NPs) to enhance paclitaxel (PTX) cytotoxicity in SKOV3 ovarian...
2.
Pai F, Lin W
Biomater Adv . 2023 Aug; 153:213577. PMID: 37572599
Functional polymeric nanoparticles (NPs) with antitumor potential were combined with the topoisomerase I inhibitor, irinotecan (IRT), to enhance cytotoxicity against colorectal cancers. The negatively charged γ-polyglutamic acid (γ-PGA) or fucoidan...
3.
He G, Lin W
Nanomaterials (Basel) . 2021 Apr; 11(3). PMID: 33803751
Seliciclib, a broad cyclin-dependent kinases (CDKs) inhibitor, exerts its potential role in cancer therapy. For taking advantage of overexpressive transferrin receptor (TfR) on most cancer cells, T7 peptide, a TfR...
4.
Huang H, Lin W
Pharmaceutics . 2020 Mar; 12(3). PMID: 32178266
Small cell lung carcinoma (SCLC) is a highly aggressive form of malignancy with rapid recurrence and poor prognosis. The dual peptide-modified nanoparticles (NPs) for improving chemotherapy against drug-resistant small cell...
5.
Lin W, Lee S
Carbohydr Polym . 2019 Mar; 212:378-386. PMID: 30832870
Current phosphate binders used for hyperphosphatemia treatment need large daily dose which make patients' compliance worse and the therapeutic efficacy may not conform the expectation. In this study, three polyacid...
6.
Lin W, Lee W
Int J Nanomedicine . 2018 Jul; 13:3989-4002. PMID: 30022822
Background: Hyaluronic acid (HA) and chondroitin sulfate (CD) are endogenous polysaccharides. In recent years, they have aroused the interest of scientists because of specific binding to CD44 receptors, which are...
7.
Alai M, Lin W, Pingale S
J Food Drug Anal . 2017 Sep; 23(3):351-358. PMID: 28911691
Diabetes mellitus is an endocrine disease in which the pancreas does not produce sufficient insulin or the body cannot effectively use the insulin it produces. Insulin therapy has been the...
8.
Lin W, Lee W, Shieh M
Carbohydr Polym . 2016 Oct; 155:101-108. PMID: 27702492
The high- and low-molecular weight hyaluronic acid (HHA and LHA) were used to conjugate with PLGA-PEG copolymers which were applied to encapsulate DOTAP/pDNA (D/P) lipoplex as a CD44-targeted micelle delivery...
9.
Lin W, Duh Y
Eur J Pharm Biopharm . 2016 Jul; 108:297-303. PMID: 27449633
The aim of this study was to develop nanostructured lipid carriers (NLCs) for transdermal delivery of acid-labile lansoprazole (LPZ). The drug loading, particle size, zeta potential, thermal behavior and stability...
10.
Alai M, Lin W
Int J Nanomedicine . 2015 Jul; 10:4029-41. PMID: 26124659
The aim of this study was to develop nanoparticles for oral delivery of an acid-labile drug, lansoprazole (LPZ), for gastric ulcer therapy. LPZ-loaded positively charged Eudragit(®) RS100 nanoparticles (ERSNPs-LPZ) and...