Wen-Ying Chen
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Explore the profile of Wen-Ying Chen including associated specialties, affiliations and a list of published articles.
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144
Citations
1634
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Recent Articles
1.
Yeh K, Kuan Y, Wu S, Chiang C, Chen C, Chen W, et al.
Environ Toxicol
. 2025 Feb;
PMID: 40013603
This research aimed to assess the potential of irigenin to attenuate blue light (BL)-induced apoptosis in human adult retinal pigment epithelial (hARPE-19) cells loaded with N-retinylidene-N-retinylethanolamine (A2E, DA50062). Furthermore, the...
2.
NMDA receptor blockade attenuates Japanese encephalitis virus infection-induced microglia activation
Chang C, Wu C, Tzeng C, Li J, Chen Y, Chen W, et al.
J Neuroinflammation
. 2024 Nov;
21(1):291.
PMID: 39511597
Neurodegeneration and neuroinflammation are key components in the pathogenesis of Japanese Encephalitis caused by Japanese Encephalitis Virus (JEV) infection. The N-methyl-D-aspartate (NMDA)-type glutamate receptor displays excitatory neurotoxic and pro-inflammatory properties...
3.
Chen W, Zhang J, Chen L, Byrne C, Targher G, Luo L, et al.
Clin Mol Hepatol
. 2024 Oct;
31(1):56-73.
PMID: 39428978
Metabolites produced as intermediaries or end-products of microbial metabolism provide crucial signals for health and diseases, such as metabolic dysfunction-associated steatotic liver disease (MASLD). These metabolites include products of the...
4.
Zhang H, Huang O, Chen L, Zhang N, Chen W, Zheng W, et al.
Ann Med
. 2024 Oct;
56(1):2410408.
PMID: 39376063
Background: Fibrotic metabolic dysfunction-associated steatohepatitis (MASH) is a condition at risk of progressing to advanced liver disease. We examined whether an innovative exhaled nitric oxide (eNO) breath test (BT) can...
5.
Ou Y, Yu T, Li J, Wu C, Wang J, Liao S, et al.
Arch Biochem Biophys
. 2024 Oct;
761:110173.
PMID: 39369835
The prognostic value of Runt-related transcription factor 2 (Runx2) and its involvement in cell growth and motility have been reported in patients diagnosed with renal cell carcinoma (RCC). Since Runx2...
6.
Yeh K, Wu S, Chiang C, Chen C, Chen W, Tseng C, et al.
Biomed Pharmacother
. 2024 Sep;
179:117346.
PMID: 39232385
Oxidative damage contributes to age-related macular degeneration. Irigenin possesses diverse pharmacologic properties, including antioxidative and antiapoptotic effects. Our in vivo experiments indicated that irigenin mitigates UVB-induced histopathologic changes and oxidative...
7.
Lu Y, Chiang C, Chen S, Hsu Y, Chen W, Chen C, et al.
Environ Toxicol Pharmacol
. 2024 May;
108:104468.
PMID: 38759849
Chlorpyrifos, widely used for pest control, is known to have various harmful effects, although its toxic effects in macrophages and the mechanisms underlying its toxicity remain unclear. The present study...
8.
Lee C, Wu S, Yang J, Chen W, Chen C, Chen H, et al.
Arch Toxicol
. 2024 Apr;
98(7):2247-2259.
PMID: 38635053
3-Bromofluoranthene (3-BrFlu) is the secondary metabolite of fluoranthene, which is classified as a polycyclic aromatic hydrocarbon, through bromination and exists in the fine particulate matter of air pollutants. Endothelial dysfunction...
9.
Jhuo C, Chen C, Tzen J, Chen W
Environ Toxicol
. 2024 Apr;
39(7):4022-4034.
PMID: 38622810
Mitochondrial dysfunction, a common cellular hallmark in both familial and sporadic forms of Parkinson's disease (PD), is assumed to play a significant role in pathologic development and progression of the...
10.
Lu Y, Chiang C, Hsu Y, Chen C, Chen W, Tseng C, et al.
Environ Toxicol
. 2024 Feb;
39(5):2970-2979.
PMID: 38314619
Cyclizine, an over-the-counter and prescription antihistamine, finds widespread application in the prevention and treatment of motion sickness, encompassing symptoms such as nausea, vomiting, dizziness, along with its effectiveness in managing...