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Wen-Jia Chen

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Articles 49
Citations 244
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Recent Articles
1.
Lan Y, Wu Z, Chen W, Yu X, Wu H, Liu J
World J Clin Oncol . 2025 Jan; 16(1):97163. PMID: 39867730
The sine oculis homeobox homolog (SIX) family, a group of transcription factors characterized by a conserved DNA-binding homology domain, plays a critical role in orchestrating embryonic development and organogenesis across...
2.
Yang Y, Chen W, Yang C, Liu J, Su Y
Int J Rheum Dis . 2025 Jan; 28(1):e70003. PMID: 39844735
No abstract available.
3.
Wu Z, Chen W, Lan Y, Fang Z, Hou Y, Yu X, et al.
J Cancer . 2024 Dec; 15(20):6754-6767. PMID: 39668818
Recent research suggests that STEAP4, a metalloreductase , plays a crucial role in various types of tumorigeneses, especially in gastrointestinal cancers. However, few oncogenes have been reported in oral squamous...
4.
Liu J, He X, Yang K, Zhao Y, Dai E, Chen W, et al.
Microbiol Spectr . 2024 Aug; 12(10):e0021624. PMID: 39162522
Respiratory tract infections are the most common triggers for heart failure in elderly people. The healthy respiratory commensal microbiota can prevent invasion by infectious pathogens and decrease the risk of...
5.
Chen W, Ye Q, Wu H, Wu Z, Lan Y, Fang Z, et al.
Heliyon . 2024 Aug; 10(15):e34949. PMID: 39157351
Breast cancer ranks as the most prevalent cancer globally, surpassing lung cancer, with recurrence/metastasis to be its main account for the cancer-related mortality. MicroRNAs (miRNAs) participate critically in various physiological...
6.
Lan Y, Wu Z, Chen W, Fang Z, Yu X, Wu H, et al.
World J Gastroenterol . 2024 Feb; 30(2):115-127. PMID: 38312115
Small nucleolar RNAs (snoRNAs) represent a class of non-coding RNAs that play pivotal roles in post-transcriptional RNA processing and modification, thereby contributing significantly to the maintenance of cellular functions related...
7.
Fang Z, Chen W, Wu Z, Hou Y, Lan Y, Wu H, et al.
World J Clin Oncol . 2024 Jan; 15(1):9-22. PMID: 38292664
Chronic inflammation is known to increase the risk of gastrointestinal cancers (GICs), the common solid tumors worldwide. Precancerous lesions, such as chronic atrophic inflammation and ulcers, are related to inflammatory...
8.
Li T, Chen W, Zhang Y, Liu W, Lin N, Liu X
Zhongguo Zhong Yao Za Zhi . 2024 Jan; 48(24):6721-6729. PMID: 38212032
This study aims to identify the novel biomarkers of cold-dampness syndrome(RA-Cold) of rheumatoid arthritis(RA) by gene set enrichment analysis(GSEA), weighted gene correlation network analysis(WGCNA), and clinical validation. Firstly, transcriptome sequencing...
9.
Chen W, Zhong H, Wu H, Hou Y, Wu Z, Fang Z, et al.
J Cancer . 2024 Jan; 15(1):192-203. PMID: 38164285
NOTCH receptor 3 (NOTCH3) and zinc finger E-box binding protein 1 (ZEB1) play important roles in breast cancer respectively. NOTCH3 maintains the luminal phenotype and inhibits epithelial-mesenchymal transition (EMT) in...
10.
Deng W, Chen W, Zhong H, Wu L, He X
Front Immunol . 2023 Nov; 14:1275427. PMID: 38035082
Atopic dermatitis (AD) is a chronic, recurrent inflammatory disease characterized by itching. The gut microbiome can help maintain skin immune homeostasis by regulating innate and adaptive immunity. Here, we report...