Wen-Hsiung Chan
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Explore the profile of Wen-Hsiung Chan including associated specialties, affiliations and a list of published articles.
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81
Citations
1012
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Recent Articles
1.
Lee Y, Wu Y, Su C, Wang B, Yang S, Lee H, et al.
Redox Biol
. 2024 Nov;
78:103427.
PMID: 39566163
Atherosclerosis caused major morbidity and mortality worldwide. Molecules possessing lipid-lowering and/or anti-inflammatory properties are potential druggable targets against atherosclerosis. We examined the anti-atherosclerotic effects of fluorescent gold nanoclusters (FANC), which...
2.
Lee C, Wang F, Huang C, Chan W
Toxicol Res (Camb)
. 2024 Oct;
13(5):tfae158.
PMID: 39371680
In view of the rapidly expanding medical and commercial applications of silver nanoparticles (AgNPs), their potential health risks and environmental effects are a significant growing concern. Earlier research by our...
3.
Lee C, Wang F, Huang C, Chan W
Toxicol Res (Camb)
. 2024 Jan;
13(1):tfad122.
PMID: 38162594
Methylmercury (MeHg) is a potent toxin that exerts deleterious effects on human health via environmental contamination. Significant effects of MeHg on neuronal development in embryogenesis have been reported. Recently, our...
4.
Lee C, Wang F, Huang C, Chan W
Toxicol Res (Camb)
. 2023 Jul;
12(3):433-445.
PMID: 37397923
Methylmercury (MeHg), a biotransformation product derived from mercury or inorganic mercury compounds in waterways, is a potent toxin that exerts hazardous effects on human health via environmental contamination. Previous studies...
5.
Huang C, Wang F, Chan W
Toxicol Res (Camb)
. 2022 Nov;
11(5):791-803.
PMID: 36337251
Brusatol, a major quassinoid extract of Bruceae fructus, is an important bioactive component with antineoplastic capacity. Several beneficial pharmacological and biological properties of brusatol have been uncovered to date, including...
6.
Huang C, Wang F, Chan W
Toxicol Res (Camb)
. 2022 Jul;
11(3):460-474.
PMID: 35782646
The health and environmental impacts of the increasing commercial use of silver nanoparticles (AgNPs) are a growing concern. Methyl mercury (MeHg) is a potent toxin that biotransforms from mercury or...
7.
Chang K, Su Y, Tsai Y, Lan K, Hsuuw Y, Kang H, et al.
Biomed J
. 2022 Feb;
45(1):179-189.
PMID: 35148258
Background: Previous studies have demonstrated that high levels of estradiol (E2) impair blastocyst implantation through effects on the endometrium; however, whether high E2 directly affects blastocysts is not well established....
8.
Huang C, Wang F, Hsuuw Y, Huang F, Chan W
Toxicol Res (Camb)
. 2021 Dec;
10(6):1211-1222.
PMID: 34956623
Alternariol (AOH) and ochratoxin A (OTA), two mycotoxins found in many foods worldwide, exhibit cytotoxicity and embryotoxicity, triggering apoptosis and cell cycle arrest in several mammalian cells and mouse embryos....
9.
Huang C, Wang F, Chan W
Toxicol Res (Camb)
. 2021 Sep;
10(4):719-732.
PMID: 34484663
Alternariol (AOH), a mycotoxin belonging to the genus , has been shown to induce cytotoxicity, including apoptosis and cell cycle arrest, in several mammalian cell types. However, its effects on...
10.
Huang C, Wang F, Chan W
Drug Chem Toxicol
. 2020 Oct;
45(4):1449-1460.
PMID: 33106064
The current study has focused on the effects of enniatin B (ENN B, a major mycotoxin produced by fungi) on early embryonic development. In analysis, mouse blastocysts were incubated in...